GESPs

 

During the last two decades, both experimental and computational approaches have been applied to identify and predict the proteins located on cell surface membranes, although each strategy has its own limitations leading to incomplete coverage and false positives. To overcome this problem and comprehensively define the human surfaceome in the genome, we integrated GESP candidates from nine independent resources, in which the cell surface proteins were identified or predicted by distinct strategies.

List of the GESPs in the human genome


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HGNC NameEnsembl Gene IDHGNC SymbolGenomic LocationCore GESP ScoreFinal GESP Score
G protein-coupled receptor 35ENSG00000178623GPR35chr2:240605431-240631259:+810
adrenoceptor alpha 1DENSG00000171873ADRA1Dchr20:4220631-4249074:-810
prokineticin receptor 2ENSG00000101292PROKR2chr20:5302040-5314369:-810
somatostatin receptor 4ENSG00000132671SSTR4chr20:23035386-23036812:+810
melanocortin 3 receptorENSG00000124089MC3Rchr20:56248732-56249815:+79
galanin receptor 3ENSG00000128310GALR3chr22:37823382-37825495:+810
melanin concentrating hormone receptor 1ENSG00000128285MCHR1chr22:40678750-40682814:+810
glutamate metabotropic receptor 7ENSG00000196277GRM7chr3:6770001-7741533:+810
oxytocin receptorENSG00000180914OXTRchr3:8750408-8769628:-811
C-C motif chemokine receptor 8ENSG00000179934CCR8chr3:39329706-39333511:+810
C-X-C motif chemokine receptor 6ENSG00000172215CXCR6chr3:45940933-45948353:+810
X-C motif chemokine receptor 1ENSG00000173578XCR1chr3:46017024-46027742:-810
C-C motif chemokine receptor 3ENSG00000183625CCR3chr3:46163604-46266706:+810
C-C motif chemokine receptor 1ENSG00000163823CCR1chr3:46201709-46208396:-811
C-C motif chemokine receptor like 2ENSG00000121797CCRL2chr3:46407163-46412997:+811
G protein-coupled receptor 62ENSG00000180929GPR62chr3:51955314-51957504:+79
G protein-coupled receptor 27ENSG00000170837GPR27chr3:71754050-71756496:+810
olfactory receptor family 5 subfamily H member 1ENSG00000231192OR5H1chr3:98132698-98133639:+79
olfactory receptor family 5 subfamily H member 15ENSG00000233412OR5H15chr3:98168700-98198138:+79
olfactory receptor family 5 subfamily K member 3ENSG00000206536OR5K3chr3:98390666-98391631:+79

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