GESPs

 

During the last two decades, both experimental and computational approaches have been applied to identify and predict the proteins located on cell surface membranes, although each strategy has its own limitations leading to incomplete coverage and false positives. To overcome this problem and comprehensively define the human surfaceome in the genome, we integrated GESP candidates from nine independent resources, in which the cell surface proteins were identified or predicted by distinct strategies.

List of the GESPs in the human genome


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HGNC NameEnsembl Gene IDHGNC SymbolGenomic LocationCore GESP ScoreFinal GESP Score
interleukin 1 receptor accessory proteinENSG00000196083IL1RAPchr3:190514051-190659750:+1220
protocadherin 7ENSG00000169851PCDH7chr4:30720415-31146805:+1318
fibroblast growth factor receptor 1ENSG00000077782FGFR1chr8:38411138-38468834:-1319
neuroligin 4 X-linkedENSG00000146938NLGN4XchrX:5840637-6228863:-1317.5
TNF receptor superfamily member 8ENSG00000120949TNFRSF8chr1:12063377-12144207:+1216.5
endothelin converting enzyme 1ENSG00000117298ECE1chr1:21217247-21345504:-1220.5
tumor associated calcium signal transducer 2ENSG00000184292TACSTD2chr1:58575423-58577773:-1215.5
adhesion G protein-coupled receptor L2ENSG00000117114ADGRL2chr1:81306160-81992436:+1321
kirre like nephrin family adhesion molecule 1ENSG00000183853KIRRELchr1:157993273-158100262:+1217.5
CD1d moleculeENSG00000158473CD1Dchr1:158179947-158184896:+1314.5
SLAM family member 6ENSG00000162739SLAMF6chr1:160485030-160523262:-1215.5
lymphocyte antigen 9ENSG00000122224LY9chr1:160796074-160828261:+1215.5
CD244 moleculeENSG00000122223CD244chr1:160830160-160862855:-1215.5
Fc fragment of IgG receptor IIIaENSG00000203747FCGR3Achr1:161541759-161550737:-1213.5
selectin PENSG00000174175SELPchr1:169588849-169630193:-1214.5
selectin LENSG00000188404SELLchr1:169690667-169711698:-1216.5
neurofascinENSG00000163531NFASCchr1:204828651-205022822:+1216.5
mannose receptor C-type 1ENSG00000260314MRC1chr10:17809344-17911170:+1216.5
neuropilin 1ENSG00000099250NRP1chr10:33177492-33336262:-1218.5
ADAM metallopeptidase domain 12ENSG00000148848ADAM12chr10:126012381-126388455:-1214.5

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