GESPs

 

During the last two decades, both experimental and computational approaches have been applied to identify and predict the proteins located on cell surface membranes, although each strategy has its own limitations leading to incomplete coverage and false positives. To overcome this problem and comprehensively define the human surfaceome in the genome, we integrated GESP candidates from nine independent resources, in which the cell surface proteins were identified or predicted by distinct strategies.

List of the GESPs in the human genome


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HGNC NameEnsembl Gene IDHGNC SymbolGenomic LocationCore GESP ScoreFinal GESP Score
polycystin 1, transient receptor potential channel interactingENSG00000008710PKD1chr16:2088710-2135898:-713.5
solute carrier family 6 member 4ENSG00000108576SLC6A4chr17:30194319-30236002:-812.5
solute carrier family 4 member 4ENSG00000080493SLC4A4chr4:71187286-71572087:+712.5
neuropeptide Y receptor Y2ENSG00000185149NPY2Rchr4:155208629-155217078:+710
glycine receptor alpha 1ENSG00000145888GLRA1chr5:151822513-151924842:-812.5
transient receptor potential cation channel subfamily V member 6ENSG00000165125TRPV6chr7:142871203-142885762:-812.5
5-hydroxytryptamine receptor 2CENSG00000147246HTR2CchrX:114584078-114910061:+811
taste 1 receptor member 3ENSG00000169962TAS1R3chr1:1331314-1335306:+810
taste 1 receptor member 1ENSG00000173662TAS1R1chr1:6555181-6579757:+811
taste 1 receptor member 2ENSG00000179002TAS1R2chr1:18839599-18859682:-811
5-hydroxytryptamine receptor 6ENSG00000158748HTR6chr1:19665287-19679562:+810
G protein-coupled receptor 3ENSG00000181773GPR3chr1:27392644-27395814:+79
prostaglandin F receptorENSG00000122420PTGFRchr1:78303884-78539749:+79
G protein-coupled receptor 61ENSG00000156097GPR61chr1:109539872-109548406:+79
cholinergic receptor nicotinic beta 2 subunitENSG00000160716CHRNB2chr1:154567781-154580026:+811.5
olfactory receptor family 6 subfamily Y member 1ENSG00000197532OR6Y1chr1:158547128-158548105:-79
olfactory receptor family 6 subfamily P member 1ENSG00000186440OR6P1chr1:158562651-158563604:-79
olfactory receptor family 6 subfamily K member 2ENSG00000196171OR6K2chr1:158699678-158700652:-79
olfactory receptor family 6 subfamily K member 3ENSG00000203757OR6K3chr1:158717168-158718163:-79
olfactory receptor family 6 subfamily K member 6ENSG00000180433OR6K6chr1:158754720-158755891:+79

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