GESPs
During the last two decades, both experimental and computational approaches have been applied to identify and predict the proteins located on cell surface membranes, although each strategy has its own limitations leading to incomplete coverage and false positives. To overcome this problem and comprehensively define the human surfaceome in the genome, we integrated GESP candidates from nine independent resources, in which the cell surface proteins were identified or predicted by distinct strategies.
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HGNC Name | Ensembl Gene ID | HGNC Symbol | Genomic Location | Core GESP Score | Final GESP Score |
polycystin 1, transient receptor potential channel interacting | ENSG00000008710 | PKD1 | chr16:2088710-2135898:- | 7 | 13.5 |
solute carrier family 6 member 4 | ENSG00000108576 | SLC6A4 | chr17:30194319-30236002:- | 8 | 12.5 |
solute carrier family 4 member 4 | ENSG00000080493 | SLC4A4 | chr4:71187286-71572087:+ | 7 | 12.5 |
neuropeptide Y receptor Y2 | ENSG00000185149 | NPY2R | chr4:155208629-155217078:+ | 7 | 10 |
glycine receptor alpha 1 | ENSG00000145888 | GLRA1 | chr5:151822513-151924842:- | 8 | 12.5 |
transient receptor potential cation channel subfamily V member 6 | ENSG00000165125 | TRPV6 | chr7:142871203-142885762:- | 8 | 12.5 |
5-hydroxytryptamine receptor 2C | ENSG00000147246 | HTR2C | chrX:114584078-114910061:+ | 8 | 11 |
taste 1 receptor member 3 | ENSG00000169962 | TAS1R3 | chr1:1331314-1335306:+ | 8 | 10 |
taste 1 receptor member 1 | ENSG00000173662 | TAS1R1 | chr1:6555181-6579757:+ | 8 | 11 |
taste 1 receptor member 2 | ENSG00000179002 | TAS1R2 | chr1:18839599-18859682:- | 8 | 11 |
5-hydroxytryptamine receptor 6 | ENSG00000158748 | HTR6 | chr1:19665287-19679562:+ | 8 | 10 |
G protein-coupled receptor 3 | ENSG00000181773 | GPR3 | chr1:27392644-27395814:+ | 7 | 9 |
prostaglandin F receptor | ENSG00000122420 | PTGFR | chr1:78303884-78539749:+ | 7 | 9 |
G protein-coupled receptor 61 | ENSG00000156097 | GPR61 | chr1:109539872-109548406:+ | 7 | 9 |
cholinergic receptor nicotinic beta 2 subunit | ENSG00000160716 | CHRNB2 | chr1:154567781-154580026:+ | 8 | 11.5 |
olfactory receptor family 6 subfamily Y member 1 | ENSG00000197532 | OR6Y1 | chr1:158547128-158548105:- | 7 | 9 |
olfactory receptor family 6 subfamily P member 1 | ENSG00000186440 | OR6P1 | chr1:158562651-158563604:- | 7 | 9 |
olfactory receptor family 6 subfamily K member 2 | ENSG00000196171 | OR6K2 | chr1:158699678-158700652:- | 7 | 9 |
olfactory receptor family 6 subfamily K member 3 | ENSG00000203757 | OR6K3 | chr1:158717168-158718163:- | 7 | 9 |
olfactory receptor family 6 subfamily K member 6 | ENSG00000180433 | OR6K6 | chr1:158754720-158755891:+ | 7 | 9 |
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