GESPs

 

During the last two decades, both experimental and computational approaches have been applied to identify and predict the proteins located on cell surface membranes, although each strategy has its own limitations leading to incomplete coverage and false positives. To overcome this problem and comprehensively define the human surfaceome in the genome, we integrated GESP candidates from nine independent resources, in which the cell surface proteins were identified or predicted by distinct strategies.

List of the GESPs in the human genome


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HGNC NameEnsembl Gene IDHGNC SymbolGenomic LocationCore GESP ScoreFinal GESP Score
myosin heavy chain 9ENSG00000100345MYH9chr22:36281281-36388018:-815
slit guidance ligand 3ENSG00000184347SLIT3chr5:168661733-169301129:-810.5
semaphorin 3CENSG00000075223SEMA3Cchr7:80742538-80922359:-910
angiopoietin 1ENSG00000154188ANGPT1chr8:107249482-107498055:-88
collagen type VI alpha 2 chainENSG00000142173COL6A2chr21:46098097-46132849:+811
complement C5a receptor 1ENSG00000197405C5AR1chr19:47290023-47322066:+713
tachykinin receptor 1ENSG00000115353TACR1chr2:75046463-75199700:-813
parathyroid hormone 1 receptorENSG00000160801PTH1Rchr3:46877746-46903799:+712
purinergic receptor P2Y1ENSG00000169860P2RY1chr3:152834693-152841439:+712
dopamine receptor D4ENSG00000069696DRD4chr11:637293-640706:+812
cholinergic receptor muscarinic 4ENSG00000180720CHRM4chr11:46385098-46386608:-812
histamine receptor H1ENSG00000196639HRH1chr3:11137093-11263557:+813
C-C motif chemokine receptor 2ENSG00000121807CCR2chr3:46353734-46360928:+812
cholecystokinin A receptorENSG00000163394CCKARchr4:26481400-26490462:-812
cannabinoid receptor 1ENSG00000118432CNR1chr6:88139864-88166359:-711
cholinergic receptor muscarinic 2ENSG00000181072CHRM2chr7:136868669-137020255:+813
melatonin receptor 1BENSG00000134640MTNR1Bchr11:92969720-92985066:+811
arginine vasopressin receptor 1AENSG00000166148AVPR1Achr12:63142759-63150942:-811
5-hydroxytryptamine receptor 2AENSG00000102468HTR2Achr13:46831550-46897076:-811
Rh family C glycoproteinENSG00000140519RHCGchr15:89471398-89496613:-812.5

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