GESPs
During the last two decades, both experimental and computational approaches have been applied to identify and predict the proteins located on cell surface membranes, although each strategy has its own limitations leading to incomplete coverage and false positives. To overcome this problem and comprehensively define the human surfaceome in the genome, we integrated GESP candidates from nine independent resources, in which the cell surface proteins were identified or predicted by distinct strategies.
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HGNC Name | Ensembl Gene ID | HGNC Symbol | Genomic Location | Core GESP Score | Final GESP Score |
interleukin 13 receptor subunit alpha 1 | ENSG00000131724 | IL13RA1 | chrX:118727572-118794539:+ | 9 | 13.5 |
SLIT and NTRK like family member 2 | ENSG00000185985 | SLITRK2 | chrX:145817832-145825842:+ | 9 | 10.5 |
tetraspanin 1 | ENSG00000117472 | TSPAN1 | chr1:46175073-46185958:+ | 9 | 11.5 |
solute carrier family 44 member 5 | ENSG00000137968 | SLC44A5 | chr1:75202131-75611116:- | 8 | 9.5 |
CD151 molecule (Raph blood group) | ENSG00000177697 | CD151 | chr11:832843-839831:+ | 9 | 16.5 |
LDL receptor related protein 5 | ENSG00000162337 | LRP5 | chr11:68312609-68449275:+ | 9 | 11.5 |
solute carrier family 36 member 4 | ENSG00000180773 | SLC36A4 | chr11:93144171-93197964:- | 8 | 9.5 |
epithelial membrane protein 1 | ENSG00000134531 | EMP1 | chr12:13196716-13219939:+ | 9 | 11.5 |
solute carrier family 2 member 13 | ENSG00000151229 | SLC2A13 | chr12:39755021-40106089:- | 9 | 13.5 |
tetraspanin 31 | ENSG00000135452 | TSPAN31 | chr12:57738013-57750211:+ | 8 | 11.5 |
potassium voltage-gated channel subfamily C member 2 | ENSG00000166006 | KCNC2 | chr12:75040077-75209868:- | 9 | 10.5 |
solute carrier family 6 member 15 | ENSG00000072041 | SLC6A15 | chr12:84859488-84913615:- | 9 | 10.5 |
solute carrier family 8 member B1 | ENSG00000089060 | SLC8B1 | chr12:113298759-113359493:- | 8 | 10.5 |
purinergic receptor P2X 1 | ENSG00000108405 | P2RX1 | chr17:3896592-3916500:- | 9 | 11.5 |
desmoglein 1 | ENSG00000134760 | DSG1 | chr18:31318089-31357029:+ | 9 | 15 |
LY6/PLAUR domain containing 3 | ENSG00000124466 | LYPD3 | chr19:43460787-43465660:- | 9 | 11.5 |
epithelial membrane protein 3 | ENSG00000142227 | EMP3 | chr19:48321509-48330553:+ | 9 | 12.5 |
leukocyte immunoglobulin like receptor A5 | ENSG00000187116 | LILRA5 | chr19:54307070-54313139:- | 8 | 9 |
leukocyte immunoglobulin like receptor A1 | ENSG00000104974 | LILRA1 | chr19:54573879-54602090:+ | 8 | 11 |
ST3 beta-galactoside alpha-2,3-sialyltransferase 5 | ENSG00000115525 | ST3GAL5 | chr2:85839144-85889014:- | 8 | 9.5 |
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