GESPs

 

During the last two decades, both experimental and computational approaches have been applied to identify and predict the proteins located on cell surface membranes, although each strategy has its own limitations leading to incomplete coverage and false positives. To overcome this problem and comprehensively define the human surfaceome in the genome, we integrated GESP candidates from nine independent resources, in which the cell surface proteins were identified or predicted by distinct strategies.

List of the GESPs in the human genome


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HGNC NameEnsembl Gene IDHGNC SymbolGenomic LocationCore GESP ScoreFinal GESP Score
contactin associated protein 1ENSG00000108797CNTNAP1chr17:42682613-42699814:+811.5
ATP binding cassette subfamily A member 8ENSG00000141338ABCA8chr17:68867292-68955392:-810.5
solute carrier family 16 member 3ENSG00000141526SLC16A3chr17:82228397-82261129:+916.5
desmoglein 3ENSG00000134757DSG3chr18:31447795-31478702:+910
interleukin 27 receptor subunit alphaENSG00000104998IL27RAchr19:14031748-14053216:+911.5
serine peptidase inhibitor, Kunitz type 2ENSG00000167642SPINT2chr19:38244035-38292614:+812.5
leucine rich repeat and fibronectin type III domain containing 1ENSG00000128011LRFN1chr19:39306568-39315336:-811.5
fukutin related proteinENSG00000181027FKRPchr19:46746046-46776988:+811.5
leucine rich repeat containing 4BENSG00000131409LRRC4Bchr19:50516892-50568045:-810.5
ADAM metallopeptidase domain 17ENSG00000151694ADAM17chr2:9488486-9555792:-815.5
interleukin 1 receptor like 2ENSG00000115598IL1RL2chr2:102186973-102240002:+89.5
interleukin 18 receptor 1ENSG00000115604IL18R1chr2:102311529-102398775:+811.5
activin A receptor type 2AENSG00000121989ACVR2Achr2:147844517-147930826:+911.5
lymphocyte antigen 75ENSG00000054219LY75chr2:159803355-159904749:-814.5
transient receptor potential cation channel subfamily M member 8ENSG00000144481TRPM8chr2:233917398-234019522:+810.5
protein tyrosine phosphatase receptor type AENSG00000132670PTPRAchr20:2864184-3039076:+813.5
prostate transmembrane protein, androgen induced 1ENSG00000124225PMEPA1chr20:57648392-57711536:-810.5
pannexin 2ENSG00000073150PANX2chr22:50170731-50180294:+910.5
interleukin 5 receptor subunit alphaENSG00000091181IL5RAchr3:3066326-3126613:-911.5
receptor like tyrosine kinaseENSG00000163785RYKchr3:134065303-134250744:-911.5

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