GESPs
During the last two decades, both experimental and computational approaches have been applied to identify and predict the proteins located on cell surface membranes, although each strategy has its own limitations leading to incomplete coverage and false positives. To overcome this problem and comprehensively define the human surfaceome in the genome, we integrated GESP candidates from nine independent resources, in which the cell surface proteins were identified or predicted by distinct strategies.
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| HGNC Name | Ensembl Gene ID | HGNC Symbol | Genomic Location | Core GESP Score | Final GESP Score |
| LDL receptor related protein 6 | ENSG00000070018 | LRP6 | chr12:12116025-12267012:- | 9 | 14.5 |
| solute carrier organic anion transporter family member 1B1 | ENSG00000134538 | SLCO1B1 | chr12:21131202-21239246:+ | 9 | 11.5 |
| solute carrier family 38 member 4 | ENSG00000139209 | SLC38A4 | chr12:46764761-46832408:- | 9 | 10.5 |
| adenylate cyclase 6 | ENSG00000174233 | ADCY6 | chr12:48766194-48789037:- | 9 | 12.5 |
| solute carrier family 39 member 5 | ENSG00000139540 | SLC39A5 | chr12:56230049-56237846:+ | 9 | 10.5 |
| potassium calcium-activated channel subfamily M regulatory beta subunit 4 | ENSG00000135643 | KCNMB4 | chr12:70366276-70434292:+ | 9 | 10.5 |
| thyrotropin releasing hormone degrading enzyme | ENSG00000072657 | TRHDE | chr12:72087266-72670757:+ | 9 | 14.5 |
| solute carrier family 41 member 2 | ENSG00000136052 | SLC41A2 | chr12:104802553-104958744:- | 9 | 10.5 |
| ATP binding cassette subfamily C member 4 | ENSG00000125257 | ABCC4 | chr13:95019829-95301446:- | 9 | 15.5 |
| C-type lectin domain containing 14A | ENSG00000176435 | CLEC14A | chr14:38254103-38256369:- | 9 | 11.5 |
| jagged canonical Notch ligand 2 | ENSG00000184916 | JAG2 | chr14:105140981-105168824:- | 8 | 10.5 |
| signal peptide peptidase like 2A | ENSG00000138600 | SPPL2A | chr15:50702266-50765808:- | 9 | 13.5 |
| neurotrophic receptor tyrosine kinase 3 | ENSG00000140538 | NTRK3 | chr15:87859751-88256768:- | 9 | 10.5 |
| semaphorin 4B | ENSG00000185033 | SEMA4B | chr15:90160604-90229679:+ | 9 | 14.5 |
| interleukin 21 receptor | ENSG00000103522 | IL21R | chr16:27402162-27452042:+ | 8 | 10.5 |
| CLN3 lysosomal/endosomal transmembrane protein, battenin | ENSG00000188603 | CLN3 | chr16:28477279-28495575:- | 8 | 10.5 |
| solute carrier family 6 member 2 | ENSG00000103546 | SLC6A2 | chr16:55655604-55706192:+ | 9 | 11.5 |
| solute carrier family 7 member 6 | ENSG00000103064 | SLC7A6 | chr16:68264516-68301823:+ | 8 | 11.5 |
| integrin subunit alpha E | ENSG00000083457 | ITGAE | chr17:3714628-3801243:- | 8 | 10.5 |
| TNF receptor superfamily member 13B | ENSG00000240505 | TNFRSF13B | chr17:16929816-16972118:- | 8 | 10.5 |
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