GESPs

 

During the last two decades, both experimental and computational approaches have been applied to identify and predict the proteins located on cell surface membranes, although each strategy has its own limitations leading to incomplete coverage and false positives. To overcome this problem and comprehensively define the human surfaceome in the genome, we integrated GESP candidates from nine independent resources, in which the cell surface proteins were identified or predicted by distinct strategies.

List of the GESPs in the human genome


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HGNC NameEnsembl Gene IDHGNC SymbolGenomic LocationCore GESP ScoreFinal GESP Score
protocadherin beta 12ENSG00000120328PCDHB12chr5:141208697-141212571:+910.5
protocadherin gamma subfamily A, 2ENSG00000081853PCDHGA2chr5:141338760-141512979:+910.5
protocadherin gamma subfamily A, 3ENSG00000254245PCDHGA3chr5:141343829-141512979:+910.5
protocadherin gamma subfamily B, 2ENSG00000253910PCDHGB2chr5:141360042-141512979:+910.5
protocadherin gamma subfamily A, 5ENSG00000253485PCDHGA5chr5:141364232-141512979:+910.5
protocadherin gamma subfamily B, 3ENSG00000262209PCDHGB3chr5:141370264-141512979:+910.5
protocadherin gamma subfamily A, 6ENSG00000253731PCDHGA6chr5:141373914-141512979:+910.5
protocadherin gamma subfamily A, 7ENSG00000253537PCDHGA7chr5:141382739-141512979:+910.5
protocadherin gamma subfamily B, 6ENSG00000253305PCDHGB6chr5:141408021-141512979:+911.5
protocadherin gamma subfamily A, 10ENSG00000253846PCDHGA10chr5:141412987-141512979:+910.5
protocadherin gamma subfamily A, 11ENSG00000253873PCDHGA11chr5:141421047-141512979:+910.5
protocadherin gamma subfamily C, 4ENSG00000242419PCDHGC4chr5:141484997-141512979:+910.5
FAT atypical cadherin 2ENSG00000086570FAT2chr5:151504093-151568944:-810.5
lymphocyte antigen 6 family member G6FENSG00000204424LY6G6Fchr6:31706885-31710595:+89.5
zona pellucida glycoprotein 3ENSG00000188372ZP3chr7:76397518-76442071:+911.5
dipeptidyl peptidase like 6ENSG00000130226DPP6chr7:153887097-154894285:+89.5
hephaestinENSG00000089472HEPHchrX:66162549-66268867:+910.5
neuroligin 3ENSG00000196338NLGN3chrX:71144831-71171201:+910.5
protocadherin 11 X-linkedENSG00000102290PCDH11XchrX:91779261-92623230:+910.5
matrix remodeling associated 8ENSG00000162576MXRA8chr1:1352689-1361777:-811.5

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