GESPs

 

During the last two decades, both experimental and computational approaches have been applied to identify and predict the proteins located on cell surface membranes, although each strategy has its own limitations leading to incomplete coverage and false positives. To overcome this problem and comprehensively define the human surfaceome in the genome, we integrated GESP candidates from nine independent resources, in which the cell surface proteins were identified or predicted by distinct strategies.

List of the GESPs in the human genome


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HGNC NameEnsembl Gene IDHGNC SymbolGenomic LocationCore GESP ScoreFinal GESP Score
claudin 7ENSG00000181885CLDN7chr17:7259903-7263983:-911.5
seizure related 6 homologENSG00000063015SEZ6chr17:28954901-29006440:-89.5
nerve growth factor receptorENSG00000064300NGFRchr17:49495293-49515017:+911.5
sidekick cell adhesion molecule 2ENSG00000069188SDK2chr17:73334384-73644089:-912
transmembrane and immunoglobulin domain containing 2ENSG00000167664TMIGD2chr19:4292232-4302431:-89.5
neurexin 1ENSG00000179915NRXN1chr2:49918505-51032561:-89.5
protein tyrosine phosphatase receptor type NENSG00000054356PTPRNchr2:219289623-219309648:-89.5
BOC cell adhesion associated, oncogene regulatedENSG00000144857BOCchr3:113211003-113287459:+89.5
immunoglobulin superfamily member 11ENSG00000144847IGSF11chr3:118900557-119146068:-89.5
solute carrier family 41 member 3ENSG00000114544SLC41A3chr3:126006355-126101561:-910.5
calsyntenin 2ENSG00000158258CLSTN2chr3:139935185-140577397:+910.5
adhesion G protein-coupled receptor A3ENSG00000152990ADGRA3chr4:22345071-22516054:-811
transient receptor potential cation channel subfamily C member 3ENSG00000138741TRPC3chr4:121879027-121951754:-912.5
toll like receptor 3ENSG00000164342TLR3chr4:186069152-186088069:+811.5
neuregulin 2ENSG00000158458NRG2chr5:139846779-140043299:-89.5
protocadherin alpha 6ENSG00000081842PCDHA6chr5:140827958-141012344:+910.5
protocadherin alpha 10ENSG00000250120PCDHA10chr5:140855883-141012344:+910.5
protocadherin beta 4ENSG00000081818PCDHB4chr5:141121799-141125623:+910.5
protocadherin beta 6ENSG00000113211PCDHB6chr5:141150022-141153287:+910.5
protocadherin beta 11ENSG00000197479PCDHB11chr5:141199582-141203779:+910.5

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