GESPs

 

During the last two decades, both experimental and computational approaches have been applied to identify and predict the proteins located on cell surface membranes, although each strategy has its own limitations leading to incomplete coverage and false positives. To overcome this problem and comprehensively define the human surfaceome in the genome, we integrated GESP candidates from nine independent resources, in which the cell surface proteins were identified or predicted by distinct strategies.

List of the GESPs in the human genome


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HGNC NameEnsembl Gene IDHGNC SymbolGenomic LocationCore GESP ScoreFinal GESP Score
CLPTM1 regulator of GABA type A receptor forward traffickingENSG00000104853CLPTM1chr19:44954585-44993341:+916.5
claudin domain containing 1ENSG00000080822CLDND1chr3:98497912-98523066:-915.5
bone marrow stromal cell antigen 1ENSG00000109743BST1chr4:15702950-15738313:+1015
hedgehog interacting proteinENSG00000164161HHIPchr4:144646021-144745271:+910.5
LMBR1 domain containing 2ENSG00000164187LMBRD2chr5:36098412-36151961:-912.5
solute carrier family 22 member 23ENSG00000137266SLC22A23chr6:3268962-3457022:-910.5
myogenesis regulating glycosidase (putative)ENSG00000164976KIAA1161chr9:34366670-34376853:-911.5
opioid binding protein/cell adhesion molecule likeENSG00000183715OPCMLchr11:132414977-133532519:-911
carboxypeptidase MENSG00000135678CPMchr12:68842197-68971570:-916
transmembrane protein 131ENSG00000075568TMEM131chr2:97756333-97995891:-910.5
calcium voltage-gated channel auxiliary subunit alpha2delta 2ENSG00000007402CACNA2D2chr3:50362799-50504244:-1012.5
CD109 moleculeENSG00000156535CD109chr6:73695785-73828316:+916.5
contactin 1ENSG00000018236CNTN1chr12:40692442-41072418:+911
tissue factor pathway inhibitorENSG00000003436TFPIchr2:187464230-187565760:-910.5
nidogen 2ENSG00000087303NID2chr14:52004803-52069228:-911
filamin AENSG00000196924FLNAchrX:154348524-154374638:-916.5
perforin 1ENSG00000180644PRF1chr10:70597348-70602775:-910
phospholipase A2 group IIIENSG00000100078PLA2G3chr22:31134809-31140607:-99
cerebral endothelial cell adhesion moleculeENSG00000167123CERCAMchr9:128411751-128437351:+910
glucagon receptorENSG00000215644GCGRchr17:81804132-81814013:+813

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