GESPs

 

During the last two decades, both experimental and computational approaches have been applied to identify and predict the proteins located on cell surface membranes, although each strategy has its own limitations leading to incomplete coverage and false positives. To overcome this problem and comprehensively define the human surfaceome in the genome, we integrated GESP candidates from nine independent resources, in which the cell surface proteins were identified or predicted by distinct strategies.

List of the GESPs in the human genome


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HGNC NameEnsembl Gene IDHGNC SymbolGenomic LocationCore GESP ScoreFinal GESP Score
family with sequence similarity 171 member A2ENSG00000161682FAM171A2chr17:44353215-44363875:-912.5
tweety family member 2ENSG00000141540TTYH2chr17:74213514-74262020:+1011.5
multiple EGF like domains 8ENSG00000105429MEGF8chr19:42325609-42378769:+912.5
CD37 moleculeENSG00000104894CD37chr19:49335171-49343335:+1014.5
cyclin and CBS domain divalent metal cation transport mediator 3ENSG00000168763CNNM3chr2:96816245-96833911:+915.5
ring finger protein 149ENSG00000163162RNF149chr2:101271219-101308701:-913.5
sodium voltage-gated channel alpha subunit 2ENSG00000136531SCN2Achr2:165239402-165392310:+1011.5
ATP binding cassette subfamily B member 11ENSG00000073734ABCB11chr2:168922938-169031322:-910.5
leucine rich repeat neuronal 1ENSG00000175928LRRN1chr3:3799437-3847703:+911.5
interleukin 17 receptor DENSG00000144730IL17RDchr3:57089982-57170306:-910
solute carrier family 15 member 2ENSG00000163406SLC15A2chr3:121894089-121944102:+1011.5
ATP binding cassette subfamily C member 5ENSG00000114770ABCC5chr3:183919934-184018015:-912.5
fibroblast growth factor receptor like 1ENSG00000127418FGFRL1chr4:1009936-1026897:+912.5
solute carrier family 2 member 9ENSG00000109667SLC2A9chr4:9771153-10054936:-913.5
gamma-aminobutyric acid type A receptor subunit alpha2ENSG00000151834GABRA2chr4:46248427-46475230:-1011.5
ephrin A5ENSG00000184349EFNA5chr5:107376889-107670895:-1011.5
thioredoxin domain containing 15ENSG00000113621TXNDC15chr5:134873803-134901525:+911.5
solute carrier family 26 member 2ENSG00000155850SLC26A2chr5:149960737-149993455:+1014.5
ADAM metallopeptidase domain 19ENSG00000135074ADAM19chr5:157395534-157575775:-912.5
MHC class I polypeptide-related sequence BENSG00000204516MICBchr6:31494881-31511124:+1013

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