GESPs

 

During the last two decades, both experimental and computational approaches have been applied to identify and predict the proteins located on cell surface membranes, although each strategy has its own limitations leading to incomplete coverage and false positives. To overcome this problem and comprehensively define the human surfaceome in the genome, we integrated GESP candidates from nine independent resources, in which the cell surface proteins were identified or predicted by distinct strategies.

List of the GESPs in the human genome


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HGNC NameEnsembl Gene IDHGNC SymbolGenomic LocationCore GESP ScoreFinal GESP Score
B and T lymphocyte associatedENSG00000186265BTLAchr3:112463968-112499561:-911.5
T cell immunoreceptor with Ig and ITIM domainsENSG00000181847TIGITchr3:114276913-114310288:+910.5
solute carrier organic anion transporter family member 2A1ENSG00000174640SLCO2A1chr3:133932696-134052184:-1011.5
sucrase-isomaltaseENSG00000090402SIchr3:164978898-165078495:-910.5
protocadherin 18ENSG00000189184PCDH18chr4:137518918-137532494:-1011.5
transmembrane 131 likeENSG00000121210KIAA0922chr4:153466346-153636711:+912.5
solute carrier family 9 member A3ENSG00000066230SLC9A3chr5:473310-524332:-1011.5
solute carrier family 12 member 7ENSG00000113504SLC12A7chr5:1050376-1112035:-914.5
cadherin 10ENSG00000040731CDH10chr5:24487100-24644978:-1011.5
cadherin 9ENSG00000113100CDH9chr5:26880600-27121150:-1011.5
solute carrier family 23 member 1ENSG00000170482SLC23A1chr5:139367196-139384553:-910.5
microfibril associated protein 3ENSG00000037749MFAP3chr5:154038906-154220478:+1012.5
solute carrier family 34 member 1ENSG00000131183SLC34A1chr5:177379235-177398848:+1011.5
homeostatic iron regulatorENSG00000010704HFEchr6:26087281-26098343:+1015.5
major histocompatibility complex, class I, FENSG00000204642HLA-Fchr6:29722775-29738528:+1015.5
major histocompatibility complex, class II, DR beta 5ENSG00000198502HLA-DRB5chr6:32517343-32530287:-914.5
major histocompatibility complex, class II, DP alpha 1ENSG00000231389HLA-DPA1chr6:33064569-33080775:-912.5
major histocompatibility complex, class II, DP beta 1ENSG00000223865HLA-DPB1chr6:33075926-33087201:+913.5
gap junction protein alpha 1ENSG00000152661GJA1chr6:121435692-121449727:+1014.5
interferon gamma receptor 1ENSG00000027697IFNGR1chr6:137197484-137219449:-1014.5

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