GESPs

 

During the last two decades, both experimental and computational approaches have been applied to identify and predict the proteins located on cell surface membranes, although each strategy has its own limitations leading to incomplete coverage and false positives. To overcome this problem and comprehensively define the human surfaceome in the genome, we integrated GESP candidates from nine independent resources, in which the cell surface proteins were identified or predicted by distinct strategies.

List of the GESPs in the human genome


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HGNC NameEnsembl Gene IDHGNC SymbolGenomic LocationCore GESP ScoreFinal GESP Score
ATPase Na+/K+ transporting subunit alpha 3ENSG00000105409ATP1A3chr19:41966582-41997497:-913.5
glutamate ionotropic receptor kainate type subunit 5ENSG00000105737GRIK5chr19:41998321-42069498:-1011.5
Fc fragment of IgG receptor and transporterENSG00000104870FCGRTchr19:49506816-49526333:+1014.5
sialic acid binding Ig like lectin 9ENSG00000129450SIGLEC9chr19:51124908-51136651:+912.5
all-trans retinoic acid induced differentiation factorENSG00000138085ATRAIDchr2:27212027-27217178:+911.5
ALK receptor tyrosine kinaseENSG00000171094ALKchr2:29192774-29921566:-1011
semaphorin 4CENSG00000168758SEMA4Cchr2:96859716-96870757:-1016.5
interleukin 1 receptor type 1ENSG00000115594IL1R1chr2:102064544-102179874:+911.5
activin A receptor type 1ENSG00000115170ACVR1chr2:157736444-157875862:-1013.5
cholinergic receptor nicotinic alpha 1 subunitENSG00000138435CHRNA1chr2:174747592-174764472:-1011.5
solute carrier family 40 member 1ENSG00000138449SLC40A1chr2:189560579-189583758:-910.5
EPH receptor A4ENSG00000116106EPHA4chr2:221418027-221574202:-1013.5
cholinergic receptor nicotinic delta subunitENSG00000135902CHRNDchr2:232525993-232536667:+1011.5
anoctamin 7ENSG00000146205ANO7chr2:241188509-241225377:+910.5
programmed cell death 1ENSG00000188389PDCD1chr2:241849881-241858908:-912.5
gamma-glutamyltransferase 7ENSG00000131067GGT7chr20:34844720-34872860:-1013.5
interleukin 10 receptor subunit betaENSG00000243646IL10RBchr21:33266358-33297234:+1014.5
transmembrane serine protease 2ENSG00000184012TMPRSS2chr21:41464551-41531116:-910.5
CUB domain containing protein 1ENSG00000163814CDCP1chr3:45082278-45146422:-914.5
chondroitin sulfate proteoglycan 5ENSG00000114646CSPG5chr3:47562239-47580792:-912.5

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