GESPs
During the last two decades, both experimental and computational approaches have been applied to identify and predict the proteins located on cell surface membranes, although each strategy has its own limitations leading to incomplete coverage and false positives. To overcome this problem and comprehensively define the human surfaceome in the genome, we integrated GESP candidates from nine independent resources, in which the cell surface proteins were identified or predicted by distinct strategies.
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| HGNC Name | Ensembl Gene ID | HGNC Symbol | Genomic Location | Core GESP Score | Final GESP Score |
| major histocompatibility complex, class I, E | ENSG00000204592 | HLA-E | chr6:30489467-30494205:+ | 9 | 12 |
| major histocompatibility complex, class I, B | ENSG00000234745 | HLA-B | chr6:31353872-31357188:- | 10 | 18 |
| advanced glycosylation end-product specific receptor | ENSG00000204305 | AGER | chr6:32180968-32184324:- | 9 | 10.5 |
| major histocompatibility complex, class II, DR alpha | ENSG00000204287 | HLA-DRA | chr6:32439842-32445046:+ | 9 | 14 |
| adhesion G protein-coupled receptor F1 | ENSG00000153292 | ADGRF1 | chr6:46997703-47042363:- | 9 | 12 |
| CF transmembrane conductance regulator | ENSG00000001626 | CFTR | chr7:117465784-117715971:+ | 10 | 13.5 |
| ADAM metallopeptidase domain 28 | ENSG00000042980 | ADAM28 | chr8:24294040-24359018:+ | 9 | 12.5 |
| signaling threshold regulating transmembrane adaptor 1 | ENSG00000137078 | SIT1 | chr9:35649295-35650950:- | 10 | 13.5 |
| transforming growth factor beta receptor 1 | ENSG00000106799 | TGFBR1 | chr9:99104038-99154192:+ | 10 | 13.5 |
| solute carrier family 31 member 1 | ENSG00000136868 | SLC31A1 | chr9:113221562-113264492:+ | 10 | 17.5 |
| angiotensin I converting enzyme 2 | ENSG00000130234 | ACE2 | chrX:15561033-15602148:- | 10 | 12.5 |
| lysosomal associated membrane protein 2 | ENSG00000005893 | LAMP2 | chrX:120427827-120469365:- | 9 | 16.5 |
| fibronectin type III domain containing 5 | ENSG00000160097 | FNDC5 | chr1:32862268-32872482:- | 10 | 11.5 |
| gap junction protein beta 3 | ENSG00000188910 | GJB3 | chr1:34781189-34786369:+ | 10 | 11.5 |
| major facilitator superfamily domain containing 2A | ENSG00000168389 | MFSD2A | chr1:39955112-39969968:+ | 10 | 11.5 |
| tyrosine kinase with immunoglobulin like and EGF like domains 1 | ENSG00000066056 | TIE1 | chr1:43300993-43323108:+ | 10 | 12.5 |
| receptor tyrosine kinase like orphan receptor 1 | ENSG00000185483 | ROR1 | chr1:63774022-64181498:+ | 10 | 14.5 |
| adhesion molecule with Ig like domain 1 | ENSG00000181754 | AMIGO1 | chr1:109504175-109509738:- | 9 | 10.5 |
| solute carrier family 16 member 1 | ENSG00000155380 | SLC16A1 | chr1:112911847-112957013:- | 10 | 18.5 |
| integrin subunit alpha 10 | ENSG00000143127 | ITGA10 | chr1:145891208-145910189:- | 9 | 10.5 |
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