GESPs

 

During the last two decades, both experimental and computational approaches have been applied to identify and predict the proteins located on cell surface membranes, although each strategy has its own limitations leading to incomplete coverage and false positives. To overcome this problem and comprehensively define the human surfaceome in the genome, we integrated GESP candidates from nine independent resources, in which the cell surface proteins were identified or predicted by distinct strategies.

List of the GESPs in the human genome


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HGNC NameEnsembl Gene IDHGNC SymbolGenomic LocationCore GESP ScoreFinal GESP Score
ADAM metallopeptidase domain 22ENSG00000008277ADAM22chr7:87934143-88202889:+1417.5
podocalyxin likeENSG00000128567PODXLchr7:131500262-131558217:-1422.5
L1 cell adhesion moleculeENSG00000198910L1CAMchrX:153861514-153909223:-1520.5
myoferlinENSG00000138119MYOFchr10:93306429-93482317:-1420.5
anoctamin 6ENSG00000177119ANO6chr12:45215987-45440404:+1419.5
solute carrier family 46 member 1ENSG00000076351SLC46A1chr17:28394756-28407197:-1418.5
integrin subunit beta 4ENSG00000132470ITGB4chr17:75721328-75757818:+1518
solute carrier family 6 member 6ENSG00000131389SLC6A6chr3:14402576-14489349:+1518.5
5'-nucleotidase ectoENSG00000135318NT5Echr6:85449584-85495791:+1421.5
solute carrier family 39 member 14ENSG00000104635SLC39A14chr8:22367249-22434129:+1523.5
Fas cell surface death receptorENSG00000026103FASchr10:88990531-89015785:+1421
calcitonin receptor like receptorENSG00000064989CALCRLchr2:187343129-187448460:-1317
cadherin EGF LAG seven-pass G-type receptor 1ENSG00000075275CELSR1chr22:46360834-46537170:-1319
protocadherin 1ENSG00000156453PCDH1chr5:141853111-141879246:-1417
MET proto-oncogene, receptor tyrosine kinaseENSG00000105976METchr7:116672390-116798386:+1421
adhesion G protein-coupled receptor G2ENSG00000173698ADGRG2chrX:18989309-19122637:-1416
sortilin 1ENSG00000134243SORT1chr1:109309568-109397951:-1320.5
CD48 moleculeENSG00000117091CD48chr1:160678746-160711851:-1317.5
F11 receptorENSG00000158769F11Rchr1:160995211-161021348:-1321.5
melanoma cell adhesion moleculeENSG00000076706MCAMchr11:119308529-119321521:-1321.5

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