GESPs

 

During the last two decades, both experimental and computational approaches have been applied to identify and predict the proteins located on cell surface membranes, although each strategy has its own limitations leading to incomplete coverage and false positives. To overcome this problem and comprehensively define the human surfaceome in the genome, we integrated GESP candidates from nine independent resources, in which the cell surface proteins were identified or predicted by distinct strategies.

List of the GESPs in the human genome


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HGNC NameEnsembl Gene IDHGNC SymbolGenomic LocationCore GESP ScoreFinal GESP Score
prostaglandin E receptor 2ENSG00000125384PTGER2chr14:52314305-52328606:+912
gamma-aminobutyric acid type A receptor subunit beta3ENSG00000166206GABRB3chr15:26543546-26939539:-1013.5
gamma-aminobutyric acid type A receptor subunit alpha5ENSG00000186297GABRA5chr15:26866363-26949207:+1013.5
somatostatin receptor 5ENSG00000162009SSTR5chr16:1078781-1080142:+1012
glucagon like peptide 2 receptorENSG00000065325GLP2Rchr17:9822206-9892102:+911
G protein-coupled receptor 142ENSG00000257008GPR142chr17:74367407-74372622:+911
sphingosine-1-phosphate receptor 4ENSG00000125910S1PR4chr19:3172346-3180332:+913
sphingosine-1-phosphate receptor 5ENSG00000180739S1PR5chr19:10512742-10517931:-912
prostaglandin I2 receptorENSG00000160013PTGIRchr19:46620468-46625118:-911
CD8b moleculeENSG00000172116CD8Bchr2:86815339-86861924:-911
G protein-coupled receptor 39ENSG00000183840GPR39chr2:132416574-132646559:+911
frizzled class receptor 7ENSG00000155760FZD7chr2:202034587-202038445:+1015
G protein-coupled receptor 156ENSG00000175697GPR156chr3:120164645-120285094:-1012
adrenoceptor alpha 2CENSG00000184160ADRA2Cchr4:3766348-3768526:+1012
neuropeptide FF receptor 2ENSG00000056291NPFFR2chr4:72031804-72148067:+1012
growth hormone receptorENSG00000112964GHRchr5:42423777-42721878:+1012.5
5-hydroxytryptamine receptor 1AENSG00000178394HTR1Achr5:63960356-63962507:-1012
adrenoceptor alpha 1BENSG00000170214ADRA1Bchr5:159916783-159972544:+1012
MAS1 proto-oncogene like, G protein-coupled receptorENSG00000204687MAS1Lchr6:29486697-29487956:-911
gamma-aminobutyric acid type B receptor subunit 1ENSG00000204681GABBR1chr6:29555629-29633976:-1012

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