GESPs

 

During the last two decades, both experimental and computational approaches have been applied to identify and predict the proteins located on cell surface membranes, although each strategy has its own limitations leading to incomplete coverage and false positives. To overcome this problem and comprehensively define the human surfaceome in the genome, we integrated GESP candidates from nine independent resources, in which the cell surface proteins were identified or predicted by distinct strategies.

List of the GESPs in the human genome


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HGNC NameEnsembl Gene IDHGNC SymbolGenomic LocationCore GESP ScoreFinal GESP Score
prostaglandin D2 receptor 2ENSG00000183134PTGDR2chr11:60850940-60855971:-1014
ATPase plasma membrane Ca2+ transporting 1ENSG00000070961ATP2B1chr12:89588049-89709300:-1021
presenilin 1ENSG00000080815PSEN1chr14:73136418-73223691:+1017.5
solute carrier family 4 member 1 (Diego blood group)ENSG00000004939SLC4A1chr17:44248385-44268141:-914.5
sphingosine-1-phosphate receptor 2ENSG00000267534S1PR2chr19:10221435-10231272:-914
gastric inhibitory polypeptide receptorENSG00000010310GIPRchr19:45668244-45683724:+912
follicle stimulating hormone receptorENSG00000170820FSHRchr2:48962157-49154537:-1012.5
gamma-aminobutyric acid type B receptor subunit 2ENSG00000136928GABBR2chr9:98288109-98709197:-1013
5-hydroxytryptamine receptor 1DENSG00000179546HTR1Dchr1:23191895-23194729:-1012
mucin 1, cell surface associatedENSG00000185499MUC1chr1:155185824-155192916:-913
G protein-coupled receptor 37 like 1ENSG00000170075GPR37L1chr1:202122858-202133592:+911
olfactory receptor family 2 subfamily C member 3ENSG00000196242OR2C3chr1:247530132-247533839:-911
tachykinin receptor 2ENSG00000075073TACR2chr10:69403903-69416867:-1012
CD81 moleculeENSG00000110651CD81chr11:2376177-2397419:+1021.5
aquaporin 5ENSG00000161798AQP5chr12:49961870-49965681:+1014.5
leucine rich repeat containing G protein-coupled receptor 5ENSG00000139292LGR5chr12:71439770-71586310:+1013
hydroxycarboxylic acid receptor 2ENSG00000182782HCAR2chr12:122701293-122703343:-911
lysophosphatidic acid receptor 6ENSG00000139679LPAR6chr13:48389567-48444704:-1013
oxoglutarate receptor 1ENSG00000165621OXGR1chr13:96985719-96994730:-911
leukotriene B4 receptor 2ENSG00000213906LTB4R2chr14:24305734-24312053:+1012

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