GESPs

 

During the last two decades, both experimental and computational approaches have been applied to identify and predict the proteins located on cell surface membranes, although each strategy has its own limitations leading to incomplete coverage and false positives. To overcome this problem and comprehensively define the human surfaceome in the genome, we integrated GESP candidates from nine independent resources, in which the cell surface proteins were identified or predicted by distinct strategies.

List of the GESPs in the human genome


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HGNC NameEnsembl Gene IDHGNC SymbolGenomic LocationCore GESP ScoreFinal GESP Score
solute carrier family 22 member 5ENSG00000197375SLC22A5chr5:132369752-132395614:+1013.5
transmembrane protein 30AENSG00000112697TMEM30Achr6:75252924-75284968:-1118.5
ectonucleotide pyrophosphatase/phosphodiesterase 3ENSG00000154269ENPP3chr6:131628442-131747418:+1013.5
synaptophysin like 1ENSG00000008282SYPL1chr7:106090503-106112576:-1119.5
lymphocyte antigen 6 family member KENSG00000160886LY6Kchr8:142700111-142705127:+1011
KIAA0319 likeENSG00000142687KIAA0319Lchr1:35433490-35557950:-1114.5
plasminogen activator, urokinase receptorENSG00000011422PLAURchr19:43646095-43670547:-1117.5
hyaluronidase 2ENSG00000068001HYAL2chr3:50317790-50322906:-1011.5
vanin 1ENSG00000112299VNN1chr6:132681590-132714049:-1011.5
melanotransferrinENSG00000163975MFI2chr3:196988621-197029816:-1016
CD14 moleculeENSG00000170458CD14chr5:140631728-140633701:-1114
thrombospondin 1ENSG00000137801THBS1chr15:39581079-39599466:+1016
endothelin receptor type BENSG00000136160EDNRBchr13:77895481-77919768:-914
C-X-C motif chemokine receptor 4ENSG00000121966CXCR4chr2:136114349-136118165:-1017.5
C-C motif chemokine receptor 5 (gene/pseudogene)ENSG00000160791CCR5chr3:46370854-46376206:+1016
glucagon like peptide 1 receptorENSG00000112164GLP1Rchr6:39048798-39087743:+915
lysophosphatidic acid receptor 1ENSG00000198121LPAR1chr9:110873263-111038458:-915
prostaglandin E receptor 3ENSG00000050628PTGER3chr1:70852353-71047808:-914
glutamate metabotropic receptor 1ENSG00000152822GRM1chr6:146027646-146437598:+1014
smoothened, frizzled class receptorENSG00000128602SMOchr7:129188872-129213545:+1016

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