GESPs

 

During the last two decades, both experimental and computational approaches have been applied to identify and predict the proteins located on cell surface membranes, although each strategy has its own limitations leading to incomplete coverage and false positives. To overcome this problem and comprehensively define the human surfaceome in the genome, we integrated GESP candidates from nine independent resources, in which the cell surface proteins were identified or predicted by distinct strategies.

List of the GESPs in the human genome


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HGNC NameEnsembl Gene IDHGNC SymbolGenomic LocationCore GESP ScoreFinal GESP Score
ssemaphorin 4FENSG00000135622SEMA4Fchr2:74654228-74683853:+1113.5
signal regulatory protein alphaENSG00000198053SIRPAchr20:1894167-1940592:+1117.5
thrombomodulinENSG00000178726THBDchr20:23045633-23049741:-1013.5
syndecan 4ENSG00000124145SDC4chr20:45325288-45348424:-1015.5
macrophage stimulating 1 receptorENSG00000164078MST1Rchr3:49887002-49903873:-1114.5
protein tyrosine phosphatase receptor type GENSG00000144724PTPRGchr3:61561569-62297613:+1017.5
CD96 moleculeENSG00000153283CD96chr3:111292719-111665750:+1013.5
CD80 moleculeENSG00000121594CD80chr3:119524293-119559602:-1113.5
podocalyxin like 2ENSG00000114631PODXL2chr3:127629181-127672809:+1014.5
glycoprotein V plateletENSG00000178732GP5chr3:194394821-194398354:-1013.5
prominin 1ENSG00000007062PROM1chr4:15963076-16084378:-1114.5
natriuretic peptide receptor 3ENSG00000113389NPR3chr5:32689070-32791724:+1013.5
teneurin transmembrane protein 2ENSG00000145934TENM2chr5:167284799-168264157:+1115.5
CD83 moleculeENSG00000112149CD83chr6:14117256-14136918:+1012.5
protein tyrosine kinase 7 (inactive)ENSG00000112655PTK7chr6:43076268-43161719:+1017.5
ectonucleotide pyrophosphatase/phosphodiesterase 4ENSG00000001561ENPP4chr6:46129993-46146699:+1013.5
vanin 2ENSG00000112303VNN2chr6:132743870-132763459:-1013.5
solute carrier family 29 member 4ENSG00000164638SLC29A4chr7:5274369-5306870:+1112.5
claudin 12ENSG00000157224CLDN12chr7:90383721-90513402:+1011.5
macrophage scavenger receptor 1ENSG00000038945MSR1chr8:16107878-16567490:-1114.5

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