GESPs

 

During the last two decades, both experimental and computational approaches have been applied to identify and predict the proteins located on cell surface membranes, although each strategy has its own limitations leading to incomplete coverage and false positives. To overcome this problem and comprehensively define the human surfaceome in the genome, we integrated GESP candidates from nine independent resources, in which the cell surface proteins were identified or predicted by distinct strategies.

List of the GESPs in the human genome


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HGNC NameEnsembl Gene IDHGNC SymbolGenomic LocationCore GESP ScoreFinal GESP Score
protein tyrosine phosphatase receptor type FENSG00000142949PTPRFchr1:43525187-43623666:+1017.5
phospholipid phosphatase 3ENSG00000162407PPAP2Bchr1:56494747-56645301:-1115.5
CD53 moleculeENSG00000143119CD53chr1:110873154-110899928:+1114.5
ATPase Na+/K+ transporting subunit alpha 1ENSG00000163399ATP1A1chr1:116372668-116410261:+1018.5
prostaglandin F2 receptor inhibitorENSG00000134247PTGFRNchr1:116910057-116990358:+1017.5
immunoglobulin superfamily member 8ENSG00000162729IGSF8chr1:160091340-160098943:-1017.5
FLVCR heme transporter 1ENSG00000162769FLVCR1chr1:212858255-212899363:+1013.5
tetraspanin 15ENSG00000099282TSPAN15chr10:69451473-69507669:+1116.5
ectonucleoside triphosphate diphosphohydrolase 1ENSG00000138185ENTPD1chr10:95711779-95877266:+1016
ATP binding cassette subfamily C member 2ENSG00000023839ABCC2chr10:99782732-99852192:+1011.5
LDL receptor related protein 4ENSG00000134569LRP4chr11:46856868-46918642:-1012.5
solute carrier family 43 member 1ENSG00000149150SLC43A1chr11:57484534-57515786:-1012.5
chromosome 11 open reading frame 24ENSG00000171067C11orf24chr11:68261335-68272001:-1012.5
myelin protein zero like 2ENSG00000149573MPZL2chr11:118253403-118264536:-1012.5
C-type lectin domain family 2 member AENSG00000188393CLEC2Achr12:9898673-9932381:-1011.5
killer cell lectin like receptor C1ENSG00000134545KLRC1chr12:10442264-10454685:-1011.5
solute carrier family 11 member 2ENSG00000110911SLC11A2chr12:50979401-51028566:-1115.5
integrin subunit alpha 5ENSG00000161638ITGA5chr12:54395261-54419460:-1018.5
CD63 moleculeENSG00000135404CD63chr12:55725323-55729707:-1115.5
plexin C1ENSG00000136040PLXNC1chr12:94148723-94307675:+1116.5

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