GESPs

 

During the last two decades, both experimental and computational approaches have been applied to identify and predict the proteins located on cell surface membranes, although each strategy has its own limitations leading to incomplete coverage and false positives. To overcome this problem and comprehensively define the human surfaceome in the genome, we integrated GESP candidates from nine independent resources, in which the cell surface proteins were identified or predicted by distinct strategies.

List of the GESPs in the human genome


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HGNC NameEnsembl Gene IDHGNC SymbolGenomic LocationCore GESP ScoreFinal GESP Score
neural cell adhesion molecule 1ENSG00000149294NCAM1chr11:112961247-113278436:+1422.5
oxidized low density lipoprotein receptor 1ENSG00000173391OLR1chr12:10158301-10172138:-1416.5
ADAM metallopeptidase domain 10ENSG00000137845ADAM10chr15:58588807-58749978:-1422.5
neogenin 1ENSG00000067141NEO1chr15:73051710-73305206:+1420.5
alanyl aminopeptidase, membraneENSG00000166825ANPEPchr15:89784889-89815401:-1520.5
cadherin 1ENSG00000039068CDH1chr16:68737225-68835548:+1518.5
cadherin 2ENSG00000170558CDH2chr18:27950966-28177446:-1522.5
desmoglein 2ENSG00000046604DSG2chr18:31498043-31549008:+1522.5
protein tyrosine phosphatase receptor type SENSG00000105426PTPRSchr19:5158495-5340803:-1419.5
PVR cell adhesion moleculeENSG00000073008PVRchr19:44643798-44663583:+1523.5
nectin cell adhesion molecule 2ENSG00000130202PVRL2chr19:44846175-44889228:+1422.5
Fc fragment of IgA receptorENSG00000186431FCARchr19:54874248-54890472:+1415.5
epithelial cell adhesion moleculeENSG00000119888EPCAMchr2:47345158-47387601:+1419.5
cadherin 4ENSG00000179242CDH4chr20:61252426-61940617:+1518.5
neural cell adhesion molecule 2ENSG00000154654NCAM2chr21:20998315-21543329:+1417.5
junctional adhesion molecule 2ENSG00000154721JAM2chr21:25639272-25717562:+1418.5
transforming growth factor beta receptor 2ENSG00000163513TGFBR2chr3:30606502-30694142:+1520.5
KIT proto-oncogene, receptor tyrosine kinaseENSG00000157404KITchr4:54657918-54740715:+1517.5
interleukin 7 receptorENSG00000168685IL7Rchr5:35852695-35879603:+1417.5
fms related receptor tyrosine kinase 4ENSG00000037280FLT4chr5:180601506-180649624:-1517.5

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