GESPs

 

During the last two decades, both experimental and computational approaches have been applied to identify and predict the proteins located on cell surface membranes, although each strategy has its own limitations leading to incomplete coverage and false positives. To overcome this problem and comprehensively define the human surfaceome in the genome, we integrated GESP candidates from nine independent resources, in which the cell surface proteins were identified or predicted by distinct strategies.

List of the GESPs in the human genome


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HGNC NameEnsembl Gene IDHGNC SymbolGenomic LocationCore GESP ScoreFinal GESP Score
insulin receptor substrate 1ENSG00000169047IRS1chr2:226731317-226799759:-44
erythrocyte membrane protein band 4.1 like 1ENSG00000088367EPB41L1chr20:36091504-36232799:+45
CDC42 effector protein 1ENSG00000128283CDC42EP1chr22:37560447-37569405:+46
microtubule associated protein 4ENSG00000047849MAP4chr3:47850690-48089272:-410
semaphorin 3GENSG00000010319SEMA3Gchr3:52433053-52445085:-44
phospholipase D1ENSG00000075651PLD1chr3:171600405-171810950:-45
diacylglycerol kinase gammaENSG00000058866DGKGchr3:186105668-186362237:-44
amphiphysinENSG00000078053AMPHchr7:38383704-38631567:-45
semaphorin 3AENSG00000075213SEMA3Achr7:83955777-84492724:-44
thyroid hormone receptor interactor 6ENSG00000087077TRIP6chr7:100867138-100873454:+48
GRIP and coiled-coil domain containing 1ENSG00000179562GCC1chr7:127580618-127593611:-44
Rho related BTB domain containing 2ENSG00000008853RHOBTB2chr8:22987417-23020199:+44
chromosome 9 open reading frame 135ENSG00000204711C9orf135chr9:69820793-69906232:+44
G protein subunit alpha qENSG00000156052GNAQchr9:77716087-78031458:-46
shroom family member 2ENSG00000146950SHROOM2chrX:9786456-9949443:+44
cerebral dopamine neurotrophic factorENSG00000185267CDNFchr10:14819250-14838575:-45
deleted in malignant brain tumors 1ENSG00000187908DMBT1chr10:122560665-122643736:+46
immunoglobulin heavy variable 4/OR15-8 (non-functional)ENSG00000259261IGHV4OR15-8chr15:22184967-22185402:-44
bone morphogenetic protein 6ENSG00000153162BMP6chr6:7726797-7881422:+44
semaphorin 3EENSG00000170381SEMA3Echr7:83363906-83649010:-44

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