GESPs

 

During the last two decades, both experimental and computational approaches have been applied to identify and predict the proteins located on cell surface membranes, although each strategy has its own limitations leading to incomplete coverage and false positives. To overcome this problem and comprehensively define the human surfaceome in the genome, we integrated GESP candidates from nine independent resources, in which the cell surface proteins were identified or predicted by distinct strategies.

List of the GESPs in the human genome


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HGNC NameEnsembl Gene IDHGNC SymbolGenomic LocationCore GESP ScoreFinal GESP Score
membrane associated guanylate kinase, WW and PDZ domain containing 2ENSG00000187391MAGI2chr7:78017057-79453574:-44
T cell receptor beta constant 1ENSG00000211751TRBV25-1chr7:142670777-142793368:+44
GTP binding protein overexpressed in skeletal muscleENSG00000164949GEMchr8:94249253-94262350:-44
activity regulated cytoskeleton associated proteinENSG00000198576ARCchr8:142611044-142614472:-44
VPS28 subunit of ESCRT-IENSG00000160948VPS28chr8:144423601-144428563:-46
membrane palmitoylated protein 1ENSG00000130830MPP1chrX:154778684-154821007:-46
membrane palmitoylated protein 7ENSG00000150054MPP7chr10:28050993-28334486:-46
growth differentiation factor 2ENSG00000263761GDF2chr10:47322490-47326270:+44
STAM binding protein like 1ENSG00000138134STAMBPL1chr10:88879734-88975153:+44
plakophilin 3ENSG00000184363PKP3chr11:392614-404908:+45
AHNAK nucleoproteinENSG00000124942AHNAKchr11:62433542-62556235:-410
folate receptor gammaENSG00000110203FOLR3chr11:72114869-72139892:+46.5
HYLS1 centriolar and ciliogenesis associatedENSG00000198331HYLS1chr11:125883614-125900648:+44
AHNAK nucleoprotein 2ENSG00000185567AHNAK2chr14:104937244-104978357:-47
RRAD, Ras related glycolysis inhibitor and calcium channel regulatorENSG00000166592RRADchr16:66921679-66925644:-45
perilipin 4ENSG00000167676PLIN4chr19:4502180-4518465:-44
homer scaffold protein 3ENSG00000051128HOMER3chr19:18929201-18941261:-47
periaxinENSG00000105227PRXchr19:40393768-40413366:-44
SH3 and multiple ankyrin repeat domains 1ENSG00000161681SHANK1chr19:50661827-50719450:-44
kallikrein related peptidase 9ENSG00000213022KLK9chr19:51003111-51009634:-44

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