GESPs

 

During the last two decades, both experimental and computational approaches have been applied to identify and predict the proteins located on cell surface membranes, although each strategy has its own limitations leading to incomplete coverage and false positives. To overcome this problem and comprehensively define the human surfaceome in the genome, we integrated GESP candidates from nine independent resources, in which the cell surface proteins were identified or predicted by distinct strategies.

List of the GESPs in the human genome


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HGNC NameEnsembl Gene IDHGNC SymbolGenomic LocationCore GESP ScoreFinal GESP Score
abl interactor 1ENSG00000136754ABI1chr10:26746593-26861087:-46.5
neuralized E3 ubiquitin protein ligase 1ENSG00000107954NEURL1chr10:103493979-103592552:+44
phosphatidylinositol-4-phosphate 3-kinase catalytic subunit type 2 alphaENSG00000011405PIK3C2Achr11:17077730-17207983:-46
Bardet-Biedl syndrome 1ENSG00000174483BBS1chr11:66510606-66533627:+45
phosphodiesterase 2AENSG00000186642PDE2Achr11:72576141-72674591:-44
protein arginine methyltransferase 8ENSG00000111218PRMT8chr12:3381349-3593973:+44
discs large MAGUK scaffold protein 4ENSG00000132535DLG4chr17:7189890-7219702:-44.5
prolyl 4-hydroxylase subunit betaENSG00000185624P4HBchr17:81843159-81860694:-410
dynamin 2ENSG00000079805DNM2chr19:10718079-10833488:+410
family with sequence similarity 126 member BENSG00000155744FAM126Bchr2:200973718-201071671:-44
phosphatidylinositol-3,4,5-trisphosphate dependent Rac exchange factor 1ENSG00000124126PREX1chr20:48624252-48827883:-46
immunoglobulin lambda like polypeptide 5ENSG00000254709IGLL5chr22:22734620-22896107:+44.5
FER tyrosine kinaseENSG00000151422FERchr5:108747822-109196841:+45
TUB like protein 1ENSG00000112041TULP1chr6:35497874-35512938:-45
LanC like 2ENSG00000132434LANCL2chr7:55365448-55433742:+47
SH2B adaptor protein 2ENSG00000160999SH2B2chr7:102285091-102321711:+44.5
nitric oxide synthase 3ENSG00000164867NOS3chr7:150990995-151014588:+44
protein tyrosine kinase 2ENSG00000169398PTK2chr8:140657900-141002216:-46
glycosylphosphatidylinositol anchored high density lipoprotein binding protein 1ENSG00000277494GPIHBP1chr8:143213193-143217170:+44
MAPK associated protein 1ENSG00000119487MAPKAP1chr9:125437393-125707234:-45

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