GESPs

 

During the last two decades, both experimental and computational approaches have been applied to identify and predict the proteins located on cell surface membranes, although each strategy has its own limitations leading to incomplete coverage and false positives. To overcome this problem and comprehensively define the human surfaceome in the genome, we integrated GESP candidates from nine independent resources, in which the cell surface proteins were identified or predicted by distinct strategies.

List of the GESPs in the human genome


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HGNC NameEnsembl Gene IDHGNC SymbolGenomic LocationCore GESP ScoreFinal GESP Score
RAS p21 protein activator 3ENSG00000185989RASA3chr13:113977783-114132611:-46.5
microtubule affinity regulating kinase 3ENSG00000075413MARK3chr14:103385392-103503831:+46.5
calcium/calmodulin dependent protein kinase II betaENSG00000058404CAMK2Bchr7:44217150-44334577:-46
DAB2 interacting proteinENSG00000136848DAB2IPchr9:121567057-121785530:+46
NEDD4 E3 ubiquitin protein ligaseENSG00000069869NEDD4chr15:55826922-55993746:-47.5
tyrosine kinase non receptor 2ENSG00000061938TNK2chr3:195863364-195911945:-45.5
polypeptide N-acetylgalactosaminyltransferase 10ENSG00000164574GALNT10chr5:154190730-154420984:+46
syndecan binding proteinENSG00000137575SDCBPchr8:58552924-58582860:+48
cell division cycle 42ENSG00000070831CDC42chr1:22052627-22092946:+410.5
LCK proto-oncogene, Src family tyrosine kinaseENSG00000182866LCKchr1:32251239-32286165:+45
deoxyribonuclease 2 betaENSG00000137976DNASE2Bchr1:84398532-84415018:+45
BMP/retinoic acid inducible neural specific 3ENSG00000162670BRINP3chr1:190097662-190478404:-44.5
cyclin YENSG00000108100CCNYchr10:35247025-35572669:+48
phosphatidylinositol 4-kinase type 2 alphaENSG00000155252PI4K2Achr10:97640686-97676434:+49
phosphatidylinositol binding clathrin assembly proteinENSG00000073921PICALMchr11:85957684-86069882:-48
Rac family small GTPase 1ENSG00000136238RAC1chr7:6374523-6403977:+411
Bardet-Biedl syndrome 9ENSG00000122507BBS9chr7:33129244-33606068:+45
G protein subunit alpha i1ENSG00000127955GNAI1chr7:80133955-80219402:+49
G protein subunit alpha i3ENSG00000065135GNAI3chr1:109548611-109618321:+411
BMP/retinoic acid inducible neural specific 2ENSG00000198797BRINP2chr1:177171497-177282422:+44.5

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