GESPs

 

During the last two decades, both experimental and computational approaches have been applied to identify and predict the proteins located on cell surface membranes, although each strategy has its own limitations leading to incomplete coverage and false positives. To overcome this problem and comprehensively define the human surfaceome in the genome, we integrated GESP candidates from nine independent resources, in which the cell surface proteins were identified or predicted by distinct strategies.

List of the GESPs in the human genome


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HGNC NameEnsembl Gene IDHGNC SymbolGenomic LocationCore GESP ScoreFinal GESP Score
jagged canonical Notch ligand 1ENSG00000101384JAG1chr20:10637684-10674107:-1116.5
cell adhesion molecule L1 likeENSG00000134121CHL1chr3:196596-409417:+1113.5
activin A receptor type 2BENSG00000114739ACVR2Bchr3:38453851-38493142:+1213.5
nectin cell adhesion molecule 3ENSG00000177707PVRL3chr3:111070071-111275563:+1216.5
heart development protein with EGF like domains 1ENSG00000173706HEG1chr3:124965710-125055958:-1117.5
plexin A1ENSG00000114554PLXNA1chr3:126988594-127037392:+1218.5
plexin D1ENSG00000004399PLXND1chr3:129555175-129606818:-1217.5
RELT like 1ENSG00000181826RELL1chr4:37590800-37686376:-1116.5
Fraser extracellular matrix complex subunit 1ENSG00000138759FRAS1chr4:78057570-78544269:+1113
toll like receptor 2ENSG00000137462TLR2chr4:153701500-153705699:+1217.5
integrin subunit alpha 1ENSG00000213949ITGA1chr5:52787896-52959210:+1118.5
integrin subunit alpha 2ENSG00000164171ITGA2chr5:52989326-53094779:+1118.5
leucyl and cystinyl aminopeptidaseENSG00000113441LNPEPchr5:96935394-97037515:+1119.5
protocadherin gamma subfamily B, 1ENSG00000254221PCDHGB1chr5:141350102-141512979:+1213.5
protocadherin gamma subfamily B, 4ENSG00000253953PCDHGB4chr5:141387698-141512979:+1214.5
protocadherin gamma subfamily A, 8ENSG00000253767PCDHGA8chr5:141390157-141512979:+1213.5
protocadherin gamma subfamily B, 5ENSG00000276547PCDHGB5chr5:141397987-141512979:+1213.5
protocadherin gamma subfamily A, 9ENSG00000261934PCDHGA9chr5:141402932-141512979:+1213.5
protocadherin gamma subfamily B, 7ENSG00000254122PCDHGB7chr5:141417645-141512979:+1213.5
protocadherin gamma subfamily A, 12ENSG00000253159PCDHGA12chr5:141430589-141512979:+1213.5

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