GESPs

 

During the last two decades, both experimental and computational approaches have been applied to identify and predict the proteins located on cell surface membranes, although each strategy has its own limitations leading to incomplete coverage and false positives. To overcome this problem and comprehensively define the human surfaceome in the genome, we integrated GESP candidates from nine independent resources, in which the cell surface proteins were identified or predicted by distinct strategies.

List of the GESPs in the human genome


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HGNC NameEnsembl Gene IDHGNC SymbolGenomic LocationCore GESP ScoreFinal GESP Score
C-type lectin domain family 12 member AENSG00000172322CLEC12Achr12:9951316-9995694:+1115.5
adhesion molecule with Ig like domain 2ENSG00000139211AMIGO2chr12:47075707-47079951:-1113.5
integrin subunit beta 7ENSG00000139626ITGB7chr12:53191318-53207307:-1215.5
protocadherin 17ENSG00000118946PCDH17chr13:57631810-57729311:+1214.5
integrin subunit alpha 11ENSG00000137809ITGA11chr15:68296533-68432162:-1115.5
neuroplastinENSG00000156642NPTNchr15:73560014-73634134:-1219.5
cadherin 5ENSG00000179776CDH5chr16:66366622-66404786:+1214.5
angiotensin I converting enzymeENSG00000159640ACEchr17:63477061-63498380:+1216.5
desmocollin 2ENSG00000134755DSC2chr18:31058840-31102415:-1215.5
TNF receptor superfamily member 11aENSG00000141655TNFRSF11Achr18:62325287-62391292:+1113.5
signal peptide peptidase like 2BENSG00000005206SPPL2Bchr19:2328615-2354806:+1215.5
cysteine rich transmembrane BMP regulator 1ENSG00000150938CRIM1chr2:36355926-36551135:+1115.5
solute carrier family 5 member 7ENSG00000115665SLC5A7chr2:107986523-108013994:+1112.5
integrin subunit beta 6ENSG00000115221ITGB6chr2:160099666-160271888:-1215.5
integrin subunit alpha 6ENSG00000091409ITGA6chr2:172427354-172506282:+1118.5
integrin subunit alpha VENSG00000138448ITGAVchr2:186590065-186680901:+1119.5
CD28 moleculeENSG00000178562CD28chr2:203706475-203738912:+1112.5
signal regulatory protein beta 1ENSG00000101307SIRPB1chr20:1563521-1620061:-1218.5
attractinENSG00000088812ATRNchr20:3471040-3651122:+1117.5
solute carrier family 23 member 2ENSG00000089057SLC23A2chr20:4852356-5010293:-1112.5

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