GESPs

 

During the last two decades, both experimental and computational approaches have been applied to identify and predict the proteins located on cell surface membranes, although each strategy has its own limitations leading to incomplete coverage and false positives. To overcome this problem and comprehensively define the human surfaceome in the genome, we integrated GESP candidates from nine independent resources, in which the cell surface proteins were identified or predicted by distinct strategies.

List of the GESPs in the human genome


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HGNC NameEnsembl Gene IDHGNC SymbolGenomic LocationCore GESP ScoreFinal GESP Score
sortilin related VPS10 domain containing receptor 1ENSG00000108018SORCS1chr10:106573663-107164534:-1213.5
zinc finger DHHC-type palmitoyltransferase 5ENSG00000156599ZDHHC5chr11:57667747-57701187:+1215.5
membrane spanning 4-domains A1ENSG00000156738MS4A1chr11:60455752-60470760:+1215.5
folate receptor alphaENSG00000110195FOLR1chr11:72189558-72196301:+1316.5
sortilin related receptor 1ENSG00000137642SORL1chr11:121452203-121633693:+1217.5
integrin subunit alpha 7ENSG00000135424ITGA7chr12:55684568-55716043:-1217.5
LDL receptor related protein 1ENSG00000123384LRP1chr12:57128493-57213351:+1219.5
purinergic receptor P2X 7ENSG00000089041P2RX7chr12:121132819-121188032:+1317.5
ATPase H+ transporting V0 subunit a2ENSG00000185344ATP6V0A2chr12:123712318-123761755:+1318.5
fms related receptor tyrosine kinase 1ENSG00000102755FLT1chr13:28300344-28495128:-1315
solute carrier family 7 member 5ENSG00000103257SLC7A5chr16:87830023-87869488:-1219.5
solute carrier family 2 member 4ENSG00000181856SLC2A4chr17:7281667-7288257:+1213.5
transient receptor potential cation channel subfamily V member 2ENSG00000187688TRPV2chr17:16415542-16437003:+1318.5
solute carrier family 39 member 6ENSG00000141424SLC39A6chr18:36108532-36129385:-1319.5
intercellular adhesion molecule 1ENSG00000090339ICAM1chr19:10270835-10286615:+1321.5
amyloid beta precursor like protein 1ENSG00000105290APLP1chr19:35867899-35879791:+1214.5
MER proto-oncogene, tyrosine kinaseENSG00000153208MERTKchr2:111898479-112029561:+1316.5
LDL receptor related protein 2ENSG00000081479LRP2chr2:169127109-169362685:-1213.5
neuropilin 2ENSG00000118257NRP2chr2:205681990-205798133:+1218.5
solute carrier organic anion transporter family member 4A1ENSG00000101187SLCO4A1chr20:62642445-62685785:+1215.5

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