TCSA Expression

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Expression

Positive expression of a GESP in a given cancer type was defined as its mRNA expression was reliably detected in at least 50% of tumor specimens (i.e., the 50th percentile of fragments per kilobase of transcript per million mapped reads [FPKM] value ≥1).

Summary of GESP mRNA expression levels (FPKM value) in each cancer type

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HGNC	Ensembl	No. Detectable	ACC				BLCA				BRCA				CESC				CHOL				COAD				DLBC				ESCA				GBM				HNSC				KICH				KIRC				KIRP				LAML				LGG				LIHC				LUAD				LUSC				MESO				OV				PAAD				PCPG				PRAD				READ				SARC				SKCM				STAD				TGCT				THCA				THYM				UCEC				UCS				UVM
Symbol	Gene ID	Cancer Types	25th	50th	75th	90th	25th	50th	75th	90th	25th	50th	75th	90th	25th	50th	75th	90th	25th	50th	75th	90th	25th	50th	75th	90th	25th	50th	75th	90th	25th	50th	75th	90th	25th	50th	75th	90th	25th	50th	75th	90th	25th	50th	75th	90th	25th	50th	75th	90th	25th	50th	75th	90th	25th	50th	75th	90th	25th	50th	75th	90th	25th	50th	75th	90th	25th	50th	75th	90th	25th	50th	75th	90th	25th	50th	75th	90th	25th	50th	75th	90th	25th	50th	75th	90th	25th	50th	75th	90th	25th	50th	75th	90th	25th	50th	75th	90th	25th	50th	75th	90th	25th	50th	75th	90th	25th	50th	75th	90th	25th	50th	75th	90th	25th	50th	75th	90th	25th	50th	75th	90th	25th	50th	75th	90th	25th	50th	75th	90th	25th	50th	75th	90th
SLC16A12	ENSG00000152779	3	0.01	0.03	0.06	0.12	0.01	0.02	0.06	0.23	0.02	0.04	0.1	0.29	0.01	0.02	0.06	0.24	0.04	0.13	0.44	0.72	0	0.01	0.03	0.05	0.01	0.02	0.03	0.05	0.01	0.02	0.05	0.14	0.06	0.12	0.23	0.32	0.01	0.02	0.04	0.08	0.51	2.43	6.65	11.97	4.63	15.74	30.87	51.15	4.87	10.42	18.51	32.17	0	0	0.01	0.02	0.02	0.04	0.08	0.18	0.06	0.19	0.77	2.5	0.08	0.22	0.63	1.84	0.03	0.06	0.12	0.26	0	0.02	0.04	0.12	0.01	0.02	0.07	0.23	0.13	0.59	1.69	3.55	0.22	0.72	3.17	5.85	0.03	0.06	0.1	0.17	0.01	0.02	0.03	0.05	0.04	0.09	0.28	0.87	0	0.01	0.03	0.06	0.02	0.04	0.07	0.15	0.08	0.15	0.34	0.67	0.36	0.87	1.84	3.74	0.03	0.19	0.61	1.19	0.09	0.38	2.28	3.71	0.07	0.15	0.32	1.1	0	0.02	0.06	0.13
OPALIN	ENSG00000197430	1	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0.01	0	0	0	0	0	0	0	0	0	0	0	0.01	0	0	0	0.01	0.05	0.24	1.68	6.83	0	0	0	0.01	0	0	0.02	0.04	0	0	0	0	0	0	0	0.01	0	0.01	0.35	1.77	0.46	2.83	11.64	28.31	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0.01	0	0	0	0	0	0	0	0	0	0	0	0.01	0	0	0	0	0	0	0	0	0	0	0	0.01	0	0	0	0	0	0	0	0.02	0	0	0	0	0	0	0	0	0.02	0.06	0.21	0.32	0	0	0	0.01	0	0	0	0.01	0	0	0	0
CALY	ENSG00000130643	4	0.02	0.06	0.33	0.92	0	0.03	0.1	0.25	0.01	0.04	0.12	0.37	0	0.03	0.09	0.19	0.03	0.08	0.13	0.63	0.01	0.05	0.13	0.28	0.03	0.08	0.14	0.2	0.01	0.05	0.12	0.27	0.43	1.61	3.59	9.19	0	0.01	0.05	0.13	0	0	0	0.04	0.01	0.04	0.1	0.19	0.01	0.05	0.12	0.34	0	0.01	0.07	0.16	1.55	4.77	15.46	38.41	0.01	0.06	0.14	0.41	0.03	0.09	0.21	0.86	0	0.04	0.11	0.27	0.05	0.12	0.59	6.98	0.03	0.08	0.27	0.72	0.51	1.44	5.08	12.83	25.15	63.64	131.85	223.91	0.1	0.18	0.34	0.58	0.02	0.07	0.15	0.26	0	0.05	0.15	0.57	0	0.03	0.09	0.23	0.05	0.12	0.38	0.96	0.28	0.73	1.6	2.58	0.03	0.09	0.24	0.67	0.03	0.08	0.17	0.36	0.02	0.09	0.25	0.72	0.09	0.24	1.13	3.4	0	0.07	0.21	0.39
OR52J3	ENSG00000205495	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0
OR4C5	ENSG00000176540	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0.04	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0
KCNE3	ENSG00000175538	32	1.89	2.83	4.99	9.47	1.19	1.86	3.48	6.96	1.32	1.9	2.64	3.55	1.19	2.04	4.18	10.32	1.63	2.63	3.44	5.82	18.64	25.63	34.19	44.19	1.88	2.43	4.51	6.36	1.43	9.82	35.47	64.07	2.65	4.09	6.73	8.28	0.67	1.34	2.6	5.16	2.51	3.64	5.86	8.05	19.72	32.11	49.2	71.81	4.06	5.57	7.62	10.32	11.65	18.42	24.69	32.93	0.64	1.01	1.74	2.95	1.1	1.65	3	4.81	3.63	5.6	9.94	16.5	3.3	5.86	14.2	28.88	1.94	2.74	3.7	5.1	4.08	6.55	11.53	19.61	5.77	12.74	24.23	44.94	1.21	2.37	6.65	15.37	0.71	1.19	2.15	4.44	19.48	25.46	35.42	38.97	2.29	4.07	6.64	11.08	0.98	1.88	3.16	4.39	15.74	29.98	58.35	94.81	2.52	3.62	5.68	8.94	1.75	3.51	7.14	11.78	0.5	0.78	1.44	2.33	2.42	4.45	9.28	20.45	2.35	3.56	5.33	9.44	0.89	1.38	1.97	2.48
CACNA1C	ENSG00000151067	17	0.28	0.6	1.41	3.61	0.42	0.84	1.71	3.63	0.93	1.66	2.84	4.43	0.19	0.37	0.74	1.42	0.61	0.81	1.49	2.42	1.4	2.8	4.83	7.15	0.11	0.26	0.45	0.75	0.9	1.74	3.21	5.56	0.64	1.22	2.06	3.12	0.31	0.59	1.06	1.9	0.28	0.38	0.69	1.13	1.2	2.2	3.47	4.9	0.11	0.2	0.42	0.85	0.15	0.3	0.61	1.91	1.64	2.52	3.63	4.68	0.12	0.25	0.54	0.95	0.62	1.04	1.81	2.8	0.46	0.82	1.36	2.29	0.82	1.38	2.18	3.61	0.28	0.56	1.05	1.88	2.76	3.84	6.64	11.68	2.86	4.18	5.89	8.07	1.56	2.62	3.91	5.1	1.46	2.21	3.9	7.09	1.45	4.39	12.14	23.25	0.24	0.41	0.78	1.6	1.06	2.24	5.47	11.85	0.61	1.11	3.49	9.94	0.51	0.82	1.11	1.59	0.5	2.31	5.5	9.95	0.31	0.65	1.5	3.06	1.1	2.43	3.95	6.94	0.15	0.24	0.41	0.63
KLRF2	ENSG00000256797	0	0	0	0	0.03	0	0	0.03	0.08	0	0	0.03	0.07	0	0.05	0.2	0.52	0	0.03	0.04	0.14	0	0	0.03	0.04	0	0	0.03	0.07	0	0	0.05	0.18	0	0	0	0.04	0	0	0.05	0.11	0	0.02	0.05	0.09	0	0.03	0.08	0.19	0	0	0.03	0.08	0	0	0.11	0.46	0	0	0	0	0	0	0	0.03	0	0	0.04	0.09	0	0	0.05	0.17	0	0	0.07	0.2	0	0	0.05	0.13	0	0.03	0.06	0.12	0	0	0	0.03	0	0	0	0.02	0	0	0	0.04	0	0	0	0.06	0	0	0	0.03	0	0	0.02	0.07	0	0	0	0.05	0	0	0.03	0.07	0.09	0.21	0.34	0.74	0	0	0.04	0.09	0	0	0	0.03	0	0	0	0
GRIN2B	ENSG00000273079	0	0	0	0	0	0	0	0.01	0.05	0	0.01	0.02	0.06	0	0	0	0.01	0	0	0	0.03	0.42	0.77	1.34	2.09	0.01	0.01	0.04	0.09	0	0.01	0.03	0.22	0.04	0.13	0.29	0.51	0	0	0	0.01	0	0	0	0.01	0	0.01	0.08	0.19	0	0.01	0.04	0.12	0	0	0	0.01	0.13	0.42	1.19	2.54	0	0	0.01	0.03	0	0	0	0.02	0	0	0.01	0.03	0	0	0.04	0.13	0	0.01	0.03	0.1	0	0.01	0.01	0.04	0	0	0.01	0.04	0	0	0	0.01	0.5	0.77	1.23	1.7	0	0	0.02	0.1	0	0.01	0.04	0.13	0	0.02	0.12	0.51	0.01	0.03	0.1	0.27	0	0	0	0.01	0	0	0	0.01	0	0.01	0.07	0.22	0.03	0.11	0.2	0.47	0.01	0.05	0.12	0.35
ACVRL1	ENSG00000139567	32	2.71	3.89	5.44	6.61	2.69	4.1	6.85	10.55	4.16	5.82	8.37	11.48	1.95	3.04	4.28	5.78	3	4.9	6.99	8.85	8.67	14.31	19.82	26.47	10.65	12.35	18.29	22.69	2.22	3.71	6.01	9.88	4.8	6.37	8.78	11.31	2.53	3.81	5.93	8.05	3.19	4.4	6.36	8.06	12.82	19.95	26.74	34.45	3.06	4.82	7.48	11.03	0.12	0.4	1.15	1.99	2.7	3.62	5.08	7.53	2.27	3.17	4.65	6.68	5.66	7.83	10.5	15.2	3.49	5.32	7.81	11.87	2.65	4.83	8.87	14.42	1.91	2.75	4.16	5.93	7.7	11.05	14.4	18.19	7.9	11.76	17.28	27.9	2.49	3.85	5.46	7.39	11.35	18.04	24.4	34.25	5.69	12.65	32.25	61.78	2.67	4.53	7.58	12.37	5.12	7.64	12.09	18.05	3.4	5.12	9.65	15.55	5.3	7.87	11.86	15.52	2.92	4.11	5.63	7.96	3.28	4.42	6.71	10.57	5.02	7.67	11.69	16.15	2.44	3.68	6.56	8.82
OR10A7	ENSG00000179919	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0.02	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0
TNFSF11	ENSG00000120659	4	0	0.01	0.04	0.13	0.11	0.25	0.58	1.23	0.18	0.41	0.76	1.57	0.11	0.28	0.81	1.61	0.28	1.34	2.32	4.72	0.63	1.33	2.93	5.03	0.21	0.85	2.33	4.34	0.19	0.45	1.09	1.64	0	0.03	0.09	0.15	0.16	0.37	0.85	1.75	0	0.01	0.03	0.06	0.04	0.1	0.3	0.85	0.01	0.04	0.12	0.34	0	0	0.05	0.13	0	0	0.01	0.03	0.06	0.22	0.64	1.41	0.2	0.44	1.21	3.07	0.24	0.47	1.03	1.65	0.06	0.13	0.32	0.75	0.03	0.08	0.21	0.48	1.26	2.36	4.42	7.24	0	0.02	0.04	0.08	0.01	0.03	0.06	0.12	0.93	1.78	2.89	4.6	0.02	0.08	0.35	1.62	0.05	0.18	0.58	1.44	0.39	0.87	1.8	3.13	0.09	0.25	0.46	0.95	0.04	0.21	0.63	1.27	0.08	0.14	0.38	1.2	0.07	0.18	0.52	1.18	0.06	0.17	0.41	0.62	0	0	0	0.02
PCDH8	ENSG00000136099	3	0	0	0.01	0.05	0	0	0.01	0.08	0	0.03	0.13	0.74	0	0.02	0.25	1.08	0	0	0	0	0	0.02	0.1	0.24	0	0	0	0.03	0	0.01	0.05	0.32	1.53	3.32	7.35	10.89	0	0	0.05	0.21	0	0	0	0.02	0	0	0	0.03	0	0	0.01	0.03	0	0	0.01	0.05	1.44	3.71	8.18	15.22	0	0	0	0	0	0	0.09	0.71	0	0.02	0.13	0.87	0	0	0.03	0.07	0	0.01	0.06	0.25	0.03	0.08	0.19	0.44	0.09	0.29	1.49	3.58	0.22	0.7	1.86	3.97	0	0.03	0.11	0.43	0	0.01	0.08	0.98	0	0	0.01	0.05	0	0.03	0.12	0.5	0.04	0.19	0.59	1.93	0.44	0.94	1.86	3	0	0.03	0.07	0.18	0	0.02	0.1	0.32	0.16	1.35	5.77	24.31	0	0	0.04	0.13
ATP4B	ENSG00000186009	0	0	0	0.01	0.02	0	0	0.01	0.03	0	0	0.01	0.03	0	0	0.02	0.04	0	0	0	0.02	0	0	0.02	0.04	0	0	0.03	0.19	0	0.01	0.03	0.11	0	0.02	0.03	0.06	0	0	0.01	0.02	0.03	0.08	0.19	0.27	0	0.01	0.03	0.06	0	0.02	0.06	0.11	0	0.02	0.06	0.11	0	0	0.01	0.03	0	0	0	0.02	0	0.03	0.07	0.16	0	0	0.01	0.04	0	0	0.01	0.02	0	0.02	0.07	0.15	0	0	0.02	0.04	0	0	0.02	0.03	0	0	0.01	0.03	0	0	0.02	0.03	0	0	0.02	0.04	0	0	0.02	0.12	0.01	0.03	0.25	4.25	0	0	0.02	0.06	0.04	0.06	0.09	0.13	0.02	0.15	0.31	0.52	0	0.02	0.09	0.32	0.03	0.04	0.18	0.51	0.02	0.05	0.12	0.46
AMN	ENSG00000166126	22	0.02	0.05	0.14	0.31	0.96	2.42	5.46	9.93	0.03	0.07	0.17	0.43	2.37	4.64	9.64	14.68	2.6	5.34	11.09	36.7	9.14	16.19	26.95	39.31	0.2	0.33	0.86	2.45	2.43	6.69	17.8	37.09	0.05	0.09	0.15	0.22	0.76	2.12	5.24	9.1	0.16	0.26	0.63	2.98	8.31	19.34	35.57	55.39	22.34	51.83	90.74	125.36	1.46	3.15	7.14	13.4	0.04	0.07	0.12	0.18	1.59	8.88	21.9	41.94	1.23	2.84	7.71	17.71	1.18	2.91	5.56	9.45	0.63	1.92	3.88	6.28	2.71	4.74	9	13.74	3.76	10.73	24.53	49.21	0.04	0.08	0.13	0.23	0.08	0.19	0.39	0.76	7.85	12.25	21.75	30.64	0.03	0.08	0.17	0.43	0.03	0.07	0.17	0.42	9.77	21.36	38.41	61.76	0.54	1.16	3.42	20.35	0.08	0.19	0.39	0.69	0.88	1.32	2.27	3.43	0.76	1.9	5.15	13.02	0.69	1.26	2.74	7.2	1.69	4.95	10.22	16.47
SLC51B	ENSG00000186198	6	0.05	0.29	0.87	2.96	0.02	0.05	0.11	0.22	0.02	0.06	0.12	0.25	0	0.04	0.12	0.56	0.14	0.35	0.98	2.08	0.95	3.24	6.83	12.88	0	0	0.04	0.06	0.05	0.12	0.39	1.08	0.26	0.53	1.09	1.75	0	0.03	0.06	0.11	0.75	1.79	4.16	8.37	0.58	1.23	2.28	4.59	1.15	2.91	9.39	20.32	0	0	0	0	0.26	0.45	0.77	1.24	1.23	3.67	9.01	22.08	0.17	0.47	1.17	3.28	0.03	0.09	0.2	0.4	0	0.02	0.07	0.09	0.05	0.11	0.28	0.94	0.09	0.16	0.29	0.62	0.23	0.52	1.58	3.28	0.17	0.28	0.47	0.8	2.13	3.84	7.41	15.65	0.03	0.16	0.71	1.56	0	0.03	0.08	0.2	0.15	0.39	1.07	4.27	0.04	0.1	0.29	1.19	0.02	0.04	0.08	0.14	0	0	0.03	0.05	0.05	0.24	0.9	2.63	0.09	0.15	0.37	1.13	0	0	0.03	0.05
SLC52A1	ENSG00000132517	6	0.01	0.02	0.04	0.13	0.38	1.08	2.42	4.45	0.16	0.38	0.86	2.17	0.79	2.39	5.8	9.16	0.04	0.08	0.39	1.02	0.09	0.21	0.49	0.86	0.13	0.3	0.86	2.64	0.24	0.79	2.49	4.07	0.07	0.14	0.25	0.51	0.72	1.49	3.05	5.48	0.02	0.04	0.13	0.52	0.03	0.07	0.21	0.86	0.19	0.98	2.73	5.4	0.03	0.05	0.1	0.16	0.03	0.05	0.09	0.17	0.01	0.02	0.05	0.11	0.32	0.93	1.99	3.2	0.8	1.82	3.55	5.94	0.04	0.1	0.2	0.41	0.07	0.12	0.26	0.53	0.07	0.13	0.27	0.54	0	0.01	0.03	0.05	0.09	0.22	0.46	0.85	0.07	0.19	0.37	0.68	0.02	0.06	0.18	0.58	0.02	0.05	0.14	0.32	0.09	0.22	0.64	1.51	0.89	1.66	3.04	4.86	0.14	0.33	0.69	1.21	1.56	4.1	7.12	10.52	0.16	0.4	1.03	2.39	0.07	0.2	0.42	0.8	0.01	0.02	0.11	0.17
TP53I13	ENSG00000167543	33	18.26	25.82	35.04	46.27	27.66	39.26	55.6	75.31	14.7	20.12	28.36	37.97	22.37	29.51	36.24	46.57	23.62	30.91	42.65	48.19	19.12	24.78	31.37	37.9	23.86	32.14	44.74	59.75	16.85	21.18	27.46	36.13	20.07	25.17	33.56	41.94	16.27	21.47	28.54	36.91	11.58	13.87	19.48	23.74	18.85	24.24	31.69	40.09	31.94	45.51	64.58	85.41	20.13	29.4	40.45	53.82	9.59	13.73	19.23	26.36	11.53	21.04	31.68	43.71	19.19	26.04	33.6	43.37	18.7	24.95	33.21	43.56	23.89	30.76	39.47	49.84	13	16.13	20.52	27.69	26.03	33.78	41.28	53.55	16	21.63	28.52	38.29	17.32	21.12	26.76	34.07	17.98	23.11	26.68	34.37	27.05	34.7	45.82	59.88	23.39	32.18	41.45	54	15.73	21.49	29.09	36.98	21.15	28.82	35.88	42.89	22.39	28.35	36.09	46.53	26.26	30.78	38.47	46.93	20.88	30.65	44.66	61.43	21.29	28.26	34.66	59.9	25.58	33.24	37.99	50.5
PLXDC1	ENSG00000161381	33	1.63	2.43	3.92	5.97	1.98	3.33	5.96	10.59	6.24	9.75	14.48	19.08	1.48	2.57	4.14	6.92	3.67	6.71	9.13	12.22	2.31	3.73	5.81	8.45	1.09	2.11	3.45	5.05	3.4	5.56	9.09	13.48	7.54	11.54	17.47	23.91	2.72	5.08	8.71	13.91	2.44	3.48	5.32	6.57	9.9	16.91	27.22	40.65	0.86	1.64	2.92	4.81	0.72	1.28	1.98	3.27	4.27	5.67	8.26	11.56	0.91	1.64	3.27	5.62	3.38	5.51	8.48	12.43	2.65	4.06	6.4	9.74	2.68	4.52	6.98	12.69	2.03	3.29	6.39	10.47	6.57	10.26	13.93	18.17	3.37	5.38	10.52	20.84	2.1	3.28	4.88	6.96	2.24	3.68	5.66	8.5	5.38	12.12	28.18	57.08	1.65	3.01	5.47	9.49	4.53	7.13	12.16	17.51	2.15	3.55	6.24	13.26	2.86	4.36	6.57	9.47	16.3	30.9	43.69	58.64	1.42	2.53	3.84	6.49	3.22	7.86	12.46	21.55	1.1	1.76	2.93	5.56
RNF43	ENSG00000108375	26	1.44	4.34	6.53	15.46	1.16	3.12	5.45	9.83	3.07	5.85	9.63	16.38	3.7	5.89	8.46	11.41	3.01	5.89	8.15	10.43	40.17	71.51	100.47	134.59	0.06	0.14	0.31	0.66	5.8	9.58	15.22	34.69	0.05	0.14	0.33	0.77	4.02	5.53	7.78	10.61	2.05	2.72	3.66	5.74	0.4	0.85	1.41	2.11	1.86	3.15	4.5	5.76	1.82	2.95	4.36	6.37	0.1	0.21	0.52	1.11	2.21	4.16	8.44	20.57	5.32	8.05	12.59	18.21	5.81	8.35	11.69	16.75	0.17	0.38	1.31	3.18	4.76	7.06	10.58	14.83	3.97	5.95	8.85	11.64	0.05	0.17	0.56	1.39	7.89	11.12	15.04	21.6	48.23	69.67	97.36	125.37	0.02	0.09	0.3	1.22	1.18	4.17	8.22	13.06	5.34	9.14	18.7	34.69	2.13	3.95	6.59	8.86	1.35	1.97	2.7	3.52	3.85	6.14	9.69	15.15	3.67	6.27	10.71	20.8	0.94	3.04	6.39	10.64	0.46	1.28	4.01	7.03

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