serine peptidase inhibitor, Kazal type 8 (putative)
Location:
3p21.31
Also known as:
Entrez ID:
646424
Ensembl ID:
ENSG00000229453
Summary:
Overall distribution
Tissue specific distribution
Expression restricted in 1 cancer type(s)
Cancer specific in breast cancer subtype (Her2; LumA)
Overall distribution
Tissue specific distribution
Gscore (Amp):
0.00
Gscore (Del):
0.16
Recurrently deleted in 1 cancer type(s)
Overall distribution
Tissue specific distribution
Mscore:
0.00
Overall
Tissue specific
Total fusion occurrence:
9
Fusions detected in 7 cancer type(s)
Overall
Tissue specific
Functional class:
Enzyme
JensenLab PubMed score:
1.00 (Percentile rank: 11.23%)
PubTator score:
NA (Percentile rank: NA)
Target development/druggability level:
TdarkThese are targets about which virtually nothing is known. They do not have known drug or small molecule activities that satisfy the activity thresholds detailed below AND satisfy two or more of the following criteria: 1) A PubMed text-mining score from Jensen Lab < 5; 2) <= 3 Gene RIFs; 3) <= 50 Antibodies available according to http://antibodypedia.com.
Tractability (small molecule):
N/A
Tractability (antibody):
Predicted Tractable - High confidenceTargets located in the plasma membrane; Targets with GO cell component terms plasma membrane or secreted
