PPP3CA
| Official symbol: | PPP3CA |
| Full name: | protein phosphatase 3 catalytic subunit alpha |
| Location: | 4q24 |
| Also known as: | CNA1, PPP2B, CALN, CALNA |
| Entrez ID: | 5530 |
| Ensembl ID: | ENSG00000138814 |
| Summary: | |
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Overall distribution
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Tissue specific distribution
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Overall distribution
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Tissue specific distribution
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| Gscore (Amp): | 0.00 | | Gscore (Del): | 0.13 |
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| Recurrently deleted in 1 cancer type(s) |
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Overall distribution
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Tissue specific distribution
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| Recurrently mutated in 1 cancer type(s) |
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Tissue specific
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| Total fusion occurrence: | 13 (Driver) |
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| Fusions detected in 3 cancer type(s) |
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| Functional class: | Enzyme |
| JensenLab PubMed score: | 997.73 (Percentile rank: 95.37%) |
| PubTator score: | 60.04 (Percentile rank: 70.62%) |
| Target development/druggability level: | TchemThese targets have activities in ChEMBL or DrugCentral that satisfy the activity thresholds detailed below. |
| Tractability (small molecule): | Predicted TractableTargets with a predicted Ro5 druggable domain (druggable genome); Targets with a drugEBIlity score equal or greater than 0 |
| Tractability (antibody): | Predicted Tractable - High confidenceTargets located in the plasma membrane; Targets with GO cell component terms plasma membrane or secreted |
