Search by PDG name  
   

 

CDK12  
    


    
      Official symbol:  CDK12
      Full name:  cyclin dependent kinase 12
      Location:  17q12
      Also known as:  CRK7, CRKR, CRKRS, KIAA0904
      Entrez ID:  51755
      Ensembl ID:  ENSG00000167258
      Summary:  

    

    
  Overall distribution
    
  Tissue specific distribution
    
 
  
 
   

    
  Overall distribution
    
  Tissue specific distribution
    
 
Gscore (Amp):  0.00  
Gscore (Del):  0.00  
 
   

    
  Overall distribution
    
  Tissue specific distribution
    
 
Mscore:  0.21  (Driver)
 
Recurrently mutated in 3 cancer type(s)
   

    
  Overall
    
  Tissue specific
    
 
Total fusion occurrence:  25  (Driver)
 
Fusions detected in 9 cancer type(s)
 
 

    
  Overall
    
  Tissue specific
    
     
   

    
      Functional class:  Kinase (protein kinase)
      JensenLab PubMed score:  29.42  (Percentile rank: 53.69%)
      PubTator score:  15.88  (Percentile rank: 48.02%)
      Target development/druggability level:  TbioThese targets do not have known drug or small molecule activities that satisfy the activity thresholds detailed below AND satisfy one or more of the following criteria: 1) target is above the cutoff criteria for Tdark; 2) target is annotated with a Gene Ontology Molecular Function or Biological Process leaf term(s) with an Experimental Evidence code.
      Tractability (small molecule):  Clinical PrecedenceTargets with drugs in phase II or above; Pre-clinical targets
      Tractability (antibody):  

    







Contact us | | Terms & Conditions.
Copyright © 2020 University of Pennsylvania. All Rights Reserved.