Mutation
The putative cancer-causing PDGs driven by somatic mutations were predicted by integration of five complementary methods to identify the genes with mutations that have significant signs of positive selection during tumor evolution.
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HGNC Symbol | Ensembl Gene ID | Overall_Mscore | No. of Cancer Types |
HSP90AA1 | ENSG00000080824 | 0.04 | 2 |
PRMT8 | ENSG00000111218 | 0.00 | 0 |
PDGFRB | ENSG00000113721 | 0.00 | 0 |
ITGB6 | ENSG00000115221 | 0.03 | 1 |
CDH5 | ENSG00000179776 | 0.00 | 0 |
PXK | ENSG00000168297 | 0.02 | 1 |
LAIR1 | ENSG00000167613 | 0.04 | 1 |
VEGFC | ENSG00000150630 | 0.00 | 0 |
ITGAL | ENSG00000005844 | 0.00 | 0 |
SLC1A5 | ENSG00000105281 | 0.00 | 0 |
ROR2 | ENSG00000169071 | 0.00 | 0 |
FBLN2 | ENSG00000163520 | 0.00 | 0 |
CD320 | ENSG00000167775 | 0.00 | 0 |
B4GALT1 | ENSG00000086062 | 0.00 | 0 |
ALPP | ENSG00000163283 | 0.03 | 1 |
ATP2C2 | ENSG00000064270 | 0.03 | 1 |
SLC26A11 | ENSG00000181045 | 0.00 | 0 |
TMX3 | ENSG00000166479 | 0.02 | 1 |
PRKCA | ENSG00000154229 | 0.03 | 1 |
EPHB4 | ENSG00000196411 | 0.00 | 0 |
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