Mutation

 

The putative cancer-causing PDGs driven by somatic mutations were predicted by integration of five complementary methods to identify the genes with mutations that have significant signs of positive selection during tumor evolution.

 

List of the putative cancer-causing PDGs driven by somatic mutations in each cancer type


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 HGNC Symbol  Ensembl Gene ID  ACC  BLCA  BRCA  CESC  CHOL  COAD  DLBC  ESCA  GBM  HNSC  KICH  KIRC  KIRP  LAML  LGG  LIHC  LUAD  LUSC  MESO  OV  PAAD  PCPG  PRAD  READ  SARC  SKCM  STAD  TGCT  THCA  THYM  UCEC  UCS  UVM 
CFTRENSG00000001626                                                                                                                                    
FLNAENSG00000196924                                                                                                                                    
FN1ENSG00000115414                                                                                                                                    
ADGRL2ENSG00000117114      1                        1                                                                                                      
VWFENSG00000110799          1                                                                                                                          
FAT4ENSG00000196159                      1                                                                                                              
BMPR2ENSG00000204217                                                                                                          1                          
CDH1ENSG00000039068          1                                                                                                1                          
ROS1ENSG00000047936                                                                                                                                    
EPHB1ENSG00000154928                                                                                                                                    
NOTCH1ENSG00000148400                                      1                    1                                                                          
CFHENSG00000000971                                                                  1    1                                                              
HMCN1ENSG00000143341                                                                                                                                    
HSP90AB1ENSG00000096384                                                                  1    1                                    1                          
GNASENSG00000087460  1                                                                                1                                                  
PLXNC1ENSG00000136040                                                                                                                                    
MYLKENSG00000065534                                      1                                                                                              
ABCA1ENSG00000165029                                                                                                                                    
F8ENSG00000185010                                                                                                                                    
ACVR1BENSG00000135503                                                                                                                                    

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