Mutation

 

The putative cancer-causing PDGs driven by somatic mutations were predicted by integration of five complementary methods to identify the genes with mutations that have significant signs of positive selection during tumor evolution.

 

List of the putative cancer-causing PDGs driven by somatic mutations in each cancer type


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 HGNC Symbol  Ensembl Gene ID  ACC  BLCA  BRCA  CESC  CHOL  COAD  DLBC  ESCA  GBM  HNSC  KICH  KIRC  KIRP  LAML  LGG  LIHC  LUAD  LUSC  MESO  OV  PAAD  PCPG  PRAD  READ  SARC  SKCM  STAD  TGCT  THCA  THYM  UCEC  UCS  UVM 
HSP90AA1ENSG00000080824                                  1            1                                                                                      
PRMT8ENSG00000111218                                                                                                                                    
PDGFRBENSG00000113721                                                                                                                                    
ITGB6ENSG00000115221      1                                                                                                                              
CDH5ENSG00000179776                                                                                                                                    
PXKENSG00000168297                                                                                                      1                              
LAIR1ENSG00000167613                                                                      1                                                              
VEGFCENSG00000150630                                                                                                                                    
ITGALENSG00000005844                                                                                                                                    
SLC1A5ENSG00000105281                                                                                                                                    
ROR2ENSG00000169071                                                                                                                                    
FBLN2ENSG00000163520                                                                                                                                    
CD320ENSG00000167775                                                                                                                                    
B4GALT1ENSG00000086062                                                                                                                                    
ALPPENSG00000163283                                                                      1                                                              
ATP2C2ENSG00000064270                                                                                                                      1              
SLC26A11ENSG00000181045                                                                                                                                    
TMX3ENSG00000166479                                                                  1                                                                  
PRKCAENSG00000154229                                                                  1                                                                  
EPHB4ENSG00000196411                                                                                                                                    

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