Mutation

 

The putative cancer-causing PDGs driven by somatic mutations were predicted by integration of five complementary methods to identify the genes with mutations that have significant signs of positive selection during tumor evolution.

 

List of the putative cancer-causing PDGs driven by somatic mutations in each cancer type


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 HGNC Symbol  Ensembl Gene ID  ACC  BLCA  BRCA  CESC  CHOL  COAD  DLBC  ESCA  GBM  HNSC  KICH  KIRC  KIRP  LAML  LGG  LIHC  LUAD  LUSC  MESO  OV  PAAD  PCPG  PRAD  READ  SARC  SKCM  STAD  TGCT  THCA  THYM  UCEC  UCS  UVM 
FGFR1ENSG00000077782                                                                  1                                                                  
CD180ENSG00000134061                                                                                                                                    
CSF1RENSG00000182578                                                                                                                                    
BACE1ENSG00000186318                                                                                                                                    
TFRCENSG00000072274                                                                                                                          1          
ECE1ENSG00000117298                                                                                                                                    
ATP1A1ENSG00000163399                                                                                                                                    
BACE2ENSG00000182240                                                                                                                                    
CD33ENSG00000105383                                                                                                                                    
PTH1RENSG00000160801                                                                                                                                    
CMKLR1ENSG00000174600                                                                                                                                    
CAMK2DENSG00000145349                                                                                                                                    
ITLN1ENSG00000179914                                                                                                                                    
PAK1ENSG00000149269                                                                                                                                    
SLC4A7ENSG00000033867                                                                      1                                                              
CD58ENSG00000116815                                                                                                                                    
HFEENSG00000010704                                                                                                                                    
CD109ENSG00000156535                                                                                                                                    
PTPRUENSG00000060656                                                                  1                                                                  
IL15RAENSG00000134470                                                                                                                                    

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