Mutation

 

The putative cancer-causing PDGs driven by somatic mutations were predicted by integration of five complementary methods to identify the genes with mutations that have significant signs of positive selection during tumor evolution.

 

List of the putative cancer-causing PDGs driven by somatic mutations in each cancer type


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 HGNC Symbol  Ensembl Gene ID  ACC  BLCA  BRCA  CESC  CHOL  COAD  DLBC  ESCA  GBM  HNSC  KICH  KIRC  KIRP  LAML  LGG  LIHC  LUAD  LUSC  MESO  OV  PAAD  PCPG  PRAD  READ  SARC  SKCM  STAD  TGCT  THCA  THYM  UCEC  UCS  UVM 
CHRM2ENSG00000181072                                                                                                                                    
MTNR1BENSG00000134640                                                                                                                                    
AVPR1AENSG00000166148                                                                                                                                    
HTR2AENSG00000102468                                                                                                                                    
RHCGENSG00000140519                                                                                                                                    
SLC6A4ENSG00000108576                                                                                                                                    
SLC4A4ENSG00000080493                                                                                                                                    
NPY2RENSG00000185149                                                                                                                                    
GLRA1ENSG00000145888                                                                                                                                    
TRPV6ENSG00000165125                                                                                                                                    
HTR2CENSG00000147246                                                                                                                                    
TAS1R3ENSG00000169962                                                                                                                                    
TAS1R1ENSG00000173662                                                                                                                                    
TAS1R2ENSG00000179002                                                                                                                                    
HTR6ENSG00000158748                                                                                                                                    
GPR3ENSG00000181773                                                                                                                                    
PTGFRENSG00000122420                                                                                                                                    
GPR61ENSG00000156097                                                                                                                                    
OR6Y1ENSG00000197532                                                                                                                                    
OR6P1ENSG00000186440                                                                                                                                    

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