Mutation

 

The putative cancer-causing PDGs driven by somatic mutations were predicted by integration of five complementary methods to identify the genes with mutations that have significant signs of positive selection during tumor evolution.

 

List of the putative cancer-causing PDGs driven by somatic mutations in each cancer type


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 HGNC Symbol  Ensembl Gene ID  ACC  BLCA  BRCA  CESC  CHOL  COAD  DLBC  ESCA  GBM  HNSC  KICH  KIRC  KIRP  LAML  LGG  LIHC  LUAD  LUSC  MESO  OV  PAAD  PCPG  PRAD  READ  SARC  SKCM  STAD  TGCT  THCA  THYM  UCEC  UCS  UVM 
GPC3ENSG00000147257                                                                                                                                    
SLC6A8ENSG00000130821                                                                                                                                    
CEACAM8ENSG00000124469                                                                                                                                    
ALPPL2ENSG00000163286                                                                                                                                    
SLIT2ENSG00000145147                                                                                                                                    
ALPIENSG00000163295                                                                                                                                    
PLAUENSG00000122861                                                                                                                                    
SLIT3ENSG00000184347                                                                                                                                    
SEMA3CENSG00000075223                                                                                                                                    
LAMC1ENSG00000135862                                                                                                                                    
COL6A2ENSG00000142173                                                                                                                                    
FGAENSG00000171560                                                                                                                                    
THBS2ENSG00000186340                                                                                                                                    
C5AR1ENSG00000197405                                                                                                                                    
TACR1ENSG00000115353                                                                                                                                    
P2RY1ENSG00000169860                                                                                                                                    
CHRM4ENSG00000180720                                                                                                                                    
CCR2ENSG00000121807                                                                                                                                    
CCKARENSG00000163394                                                                                                                                    
CNR1ENSG00000118432                                                                                                                                    

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