Mutation

 

The putative cancer-causing PDGs driven by somatic mutations were predicted by integration of five complementary methods to identify the genes with mutations that have significant signs of positive selection during tumor evolution.

 

List of the putative cancer-causing PDGs driven by somatic mutations in each cancer type


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 HGNC Symbol  Ensembl Gene ID  ACC  BLCA  BRCA  CESC  CHOL  COAD  DLBC  ESCA  GBM  HNSC  KICH  KIRC  KIRP  LAML  LGG  LIHC  LUAD  LUSC  MESO  OV  PAAD  PCPG  PRAD  READ  SARC  SKCM  STAD  TGCT  THCA  THYM  UCEC  UCS  UVM 
ADCY6ENSG00000174233                                                                                                                                    
PMELENSG00000185664                                                                                                                                    
SLC39A5ENSG00000139540                                                                                                                                    
TRHDEENSG00000072657                                                                                                                                    
SLC41A2ENSG00000136052                                                                                                                                    
CLEC14AENSG00000176435                                                                                                                                    
SPPL2AENSG00000138600                                                                                                                                    
NTRK3ENSG00000140538                                                                                                                                    
IL21RENSG00000103522                                                                                                                                    
SLC6A2ENSG00000103546                                                                                                                                    
TNFRSF13BENSG00000240505                                                                                                                                    
CNTNAP1ENSG00000108797                                                                                                                                    
ABCA8ENSG00000141338                                                                                                                                    
LRRC4BENSG00000131409                                                                                                                                    
IL1RL2ENSG00000115598                                                                                                                                    
IL18R1ENSG00000115604                                                                                                                                    
LY75ENSG00000054219                                                                                                                                    
TRPM8ENSG00000144481                                                                                                                                    
IL5RAENSG00000091181                                                                                                                                    
RYKENSG00000163785                                                                                                                                    

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