Mutation

 

The putative cancer-causing PDGs driven by somatic mutations were predicted by integration of five complementary methods to identify the genes with mutations that have significant signs of positive selection during tumor evolution.

 

List of the putative cancer-causing PDGs driven by somatic mutations in each cancer type


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 HGNC Symbol  Ensembl Gene ID  ACC  BLCA  BRCA  CESC  CHOL  COAD  DLBC  ESCA  GBM  HNSC  KICH  KIRC  KIRP  LAML  LGG  LIHC  LUAD  LUSC  MESO  OV  PAAD  PCPG  PRAD  READ  SARC  SKCM  STAD  TGCT  THCA  THYM  UCEC  UCS  UVM 
CSF2RAENSG00000198223                                                                                                      1                              
NLGN4XENSG00000146938                                                                                                                                    
TLR8ENSG00000101916                                                                                                                                    
PTPRKENSG00000152894                                                                                                                                    
IGF1RENSG00000140443                                                                                                                                    
HLA-BENSG00000234745              1                        1                                                                    1                1          
ADAM22ENSG00000008277                                                                                                                                    
SEMA4DENSG00000187764                                                                                                                                    
CNTN1ENSG00000018236                                                                                                                                    
ITPR1ENSG00000150995          1                                                                                                                          
CASRENSG00000036828                                                                                                      1                              
BCHEENSG00000114200                                                                                                                                    
C9ENSG00000113600                                                                                                      1                              
HSP90B1ENSG00000166598                                                                                                                                    
ANOS1ENSG00000011201                                                                                                          1                          
MARK3ENSG00000075413                                                                                                                                    
SLC4A8ENSG00000050438                                                                                                                                    
SLC4A2ENSG00000164889                                                                                                                                    
FAPENSG00000078098                                                                                                                                    
PTPRNENSG00000054356                                                                                                                                    

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