Mutation

 

The putative cancer-causing PDGs driven by somatic mutations were predicted by integration of five complementary methods to identify the genes with mutations that have significant signs of positive selection during tumor evolution.

 

List of the putative cancer-causing PDGs driven by somatic mutations in each cancer type


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 HGNC Symbol  Ensembl Gene ID  ACC  BLCA  BRCA  CESC  CHOL  COAD  DLBC  ESCA  GBM  HNSC  KICH  KIRC  KIRP  LAML  LGG  LIHC  LUAD  LUSC  MESO  OV  PAAD  PCPG  PRAD  READ  SARC  SKCM  STAD  TGCT  THCA  THYM  UCEC  UCS  UVM 
SYKENSG00000165025                                                                                                                                    
LEPRENSG00000116678                                                                      1                                                              
TNK2ENSG00000061938                                                                                                                          1          
F9ENSG00000101981                                                                                                      1                              
PTK2ENSG00000169398                                                                                                                                    
ATP7AENSG00000165240                                                                                                                                    
HLA-AENSG00000206503                                      1                                                                                              
FLT1ENSG00000102755                                                                                                      1                              
ACVR1ENSG00000115170                                                                                                                          1          
NOS1ENSG00000089250                                                                                                                                    
PTPRFENSG00000142949                                                                      1                                                              
ALKENSG00000171094                                                                                                                                    
CLCN5ENSG00000171365                                                                                                                                    
LCKENSG00000182866                                                                                                                                    
SLC12A2ENSG00000064651                                                                                                                                    
ENPEPENSG00000138792                                                                                                                                    
TUSC3ENSG00000104723                                                                  1                                                                  
ERBB2IPENSG00000112851                                                                                                                          1          
CPENSG00000047457                                                                                                                                    
IL4RENSG00000077238                                                                                                      1                              

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