Mutation

 

The putative cancer-causing PDGs driven by somatic mutations were predicted by integration of five complementary methods to identify the genes with mutations that have significant signs of positive selection during tumor evolution.

 

List of the putative cancer-causing PDGs driven by somatic mutations in each cancer type


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 HGNC Symbol  Ensembl Gene ID  ACC  BLCA  BRCA  CESC  CHOL  COAD  DLBC  ESCA  GBM  HNSC  KICH  KIRC  KIRP  LAML  LGG  LIHC  LUAD  LUSC  MESO  OV  PAAD  PCPG  PRAD  READ  SARC  SKCM  STAD  TGCT  THCA  THYM  UCEC  UCS  UVM 
CHRNB2ENSG00000160716                                                                                                                                    
PTGER4ENSG00000171522                                                                                                                                    
PTPRHENSG00000080031                                                                                                                                    
PIK3IP1ENSG00000100100                                                                                                                                    
KCNJ2ENSG00000123700                                                                                                                                    
SERPINI1ENSG00000163536                                                                                                                                    
LGR4ENSG00000205213                                                                                                                                    
LYNENSG00000254087                                                                                                                                    
MFGE8ENSG00000140545                                                                                                                                    
LAMP3ENSG00000078081                                                                                                                                    
CLUL1ENSG00000079101                                                                                                                                    
SV2BENSG00000185518                                                                                                                                    
CD82ENSG00000085117                                                                                                                                    
IL2RAENSG00000134460                                                                                                                                    
PRLRENSG00000113494                                                                                                                                    
SLC6A16ENSG00000063127                                                                                                                                    
CPQENSG00000104324                                                                                                                                    
SLCO3A1ENSG00000176463                                                                                                                                    
APOBENSG00000084674                                                                                                                                    
YES1ENSG00000176105                                                                                                                                    

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