Mutation

 

The putative cancer-causing PDGs driven by somatic mutations were predicted by integration of five complementary methods to identify the genes with mutations that have significant signs of positive selection during tumor evolution.

 

List of the putative cancer-causing PDGs driven by somatic mutations in each cancer type


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 HGNC Symbol  Ensembl Gene ID  ACC  BLCA  BRCA  CESC  CHOL  COAD  DLBC  ESCA  GBM  HNSC  KICH  KIRC  KIRP  LAML  LGG  LIHC  LUAD  LUSC  MESO  OV  PAAD  PCPG  PRAD  READ  SARC  SKCM  STAD  TGCT  THCA  THYM  UCEC  UCS  UVM 
APODENSG00000189058                                                                                                                                    
LMTK2ENSG00000164715                                                                                                                                    
PKN1ENSG00000123143                                                                                                                                    
GGCXENSG00000115486                                                                                                                                    
CD83ENSG00000112149                                                                                                                                    
PDGFRAENSG00000134853                                                                                                                                    
PSCAENSG00000167653                                                                                                                                    
MRC2ENSG00000011028                                                                                                                                    
PVRENSG00000073008                                                                                                                                    
PVRL2ENSG00000130202                                                                                                                                    
MMP16ENSG00000156103                                                                                                                                    
ABCA6ENSG00000154262                                                                                                                                    
GPC5ENSG00000179399                                                                                                                                    
KLK4ENSG00000167749                                                                                                                                    
KLK15ENSG00000174562                                                                                                                                    
IL6RENSG00000160712                                                                                                                                    
SLCO5A1ENSG00000137571                                                                                                                                    
LY96ENSG00000154589                                                                                                                                    
ABCA10ENSG00000154263                                                                                                                                    
CREG1ENSG00000143162                                                                                                                                    

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