Mutation

 

The putative cancer-causing PDGs driven by somatic mutations were predicted by integration of five complementary methods to identify the genes with mutations that have significant signs of positive selection during tumor evolution.

 

List of the putative cancer-causing PDGs driven by somatic mutations in each cancer type


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 HGNC Symbol  Ensembl Gene ID  ACC  BLCA  BRCA  CESC  CHOL  COAD  DLBC  ESCA  GBM  HNSC  KICH  KIRC  KIRP  LAML  LGG  LIHC  LUAD  LUSC  MESO  OV  PAAD  PCPG  PRAD  READ  SARC  SKCM  STAD  TGCT  THCA  THYM  UCEC  UCS  UVM 
TRIM28ENSG00000130726                                                                                                                                    
ATAD2BENSG00000119778          1                            1                                                                                              
ASXL2ENSG00000143970      1                        1                                                                                                      
MTA3ENSG00000057935                                                                                                                                    
SMYD5ENSG00000135632                                                                                                                                    
KDM3AENSG00000115548                                                                                                      1                              
SMYD1ENSG00000115593                                                                                                                                    
MBD5ENSG00000204406                                                                                                                                    
BAZ2BENSG00000123636                                                                                                      1                              
HAT1ENSG00000128708                                                                                                                                    
SP110ENSG00000135899                                                                                                                                    
SP140ENSG00000079263                                                                                                                                    
SP140LENSG00000185404                                      1                                                                                              
SP100ENSG00000067066                                                                                                                                    
ING5ENSG00000168395                                                                                                                                    
ASXL1ENSG00000171456                                                                                                                                    
PHF20ENSG00000025293                                                                                                                          1          
ZMYND8ENSG00000101040                                                                                                                                    
DIDO1ENSG00000101191          1                                                                                                                          
BRWD1ENSG00000185658                                                                                                      1                              

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