Mutation

 

The putative cancer-causing PDGs driven by somatic mutations were predicted by integration of five complementary methods to identify the genes with mutations that have significant signs of positive selection during tumor evolution.

 

List of the putative cancer-causing PDGs driven by somatic mutations in each cancer type


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 HGNC Symbol  Ensembl Gene ID  ACC  BLCA  BRCA  CESC  CHOL  COAD  DLBC  ESCA  GBM  HNSC  KICH  KIRC  KIRP  LAML  LGG  LIHC  LUAD  LUSC  MESO  OV  PAAD  PCPG  PRAD  READ  SARC  SKCM  STAD  TGCT  THCA  THYM  UCEC  UCS  UVM 
BTN2A2ENSG00000124508                                                                                                                                    
PTPRBENSG00000127329                                                                                                                                    
ABCC3ENSG00000108846                                                                  1                                                                  
CD44ENSG00000026508                                                                                                                                    
SLC11A1ENSG00000018280                                                                  1                                                                  
NTRK1ENSG00000198400                                                              1                                                                      
AQP1ENSG00000240583                                                                                                                                    
ADAM15ENSG00000143537                                                                                                                                    
SELLENSG00000188404                                                                  1                                    1                              
PSEN1ENSG00000080815                                                                                                                                    
DAGLBENSG00000164535                                                                                                                                    
SLC2A1ENSG00000117394                                                                                                                                    
HCN3ENSG00000143630                                                                                                                                    
PKN2ENSG00000065243          1                                                                                                                          
PI4KAENSG00000241973          1                                                                                                                          
MUC1ENSG00000185499                                                                                                                                    
ITGB4ENSG00000132470          1                                                                                                                          
KCNK1ENSG00000135750                                                                                                                                    
ITGA6ENSG00000091409                                                                                                                                    
GPIENSG00000105220                                                                                                                                    

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