Transcript Fusion
The transcript fusion data of TCGA were retrieved from the TumorFusions database.
List of the transcript fusions of the HAMPs in each cancer type
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Cancer Type | TCGA_barcode | Patient | Fusion_transcript | Gene_A | Gene_B | Chr_A | Chr_B | Strand_A | Strand_B | #_Discordant_Pairs | #_JSR | #_perfect_JSR | Evalue | Junction_A | Junction_B | Tier | Frame | TN | WGS_validation | Centrality |
LAML | TCGA-AB-2956-03A | TCGA-AB-2956 | MLL|MLLT3 | MLL | MLLT3 | 11 | 9 | 1 | -1 | 9 | 10 | 9 | 1.2 | 118353210 | 20365742 | tier1 | In-frame | 10455 | NA | 0.38125 |
LAML | TCGA-AB-2883-03A | TCGA-AB-2883 | MLL|MLLT4 | MLL | MLLT4 | 11 | 6 | 1 | 1 | 13 | 16 | 16 | 0.38 | 118355029 | 168265231 | tier1 | In-frame | 10456 | NA | 0.39579 |
LAML | TCGA-AB-2893-03A | TCGA-AB-2893 | MLL|MLLT4 | MLL | MLLT4 | 11 | 6 | 1 | 1 | 10 | 11 | 11 | 0.38 | 118353210 | 168265231 | tier4 | In-frame | 10457 | NA | 0.39579 |
LGG | TCGA-DU-A7T6-01A | TCGA-DU-A7T6 | MLL|IGHMBP2 | MLL | IGHMBP2 | 11 | 11 | 1 | 1 | 4 | 6 | 5 | 8.2 | 118382740 | 68685204 | tier1 | Out-of-frame | 10450 | NA | 0.38049 |
LUAD | TCGA-97-8174-01A | TCGA-97-8174 | MLL|FYN | MLL | FYN | 11 | 6 | 1 | -1 | 14 | 19 | 18 | 0.004 | 118382740 | 112025305 | tier1 | Out-of-frame | 10449 | NA | 0.39684 |
SKCM | TCGA-EB-A4XL-01A | TCGA-EB-A4XL | MLL|ZDHHC7 | MLL | ZDHHC7 | 11 | 16 | 1 | -1 | 9 | 5 | 4 | 2 | 118307659 | 85010831 | tier1 | Out-of-frame | 10459 | NA | 0.37997 |
BRCA | TCGA-LL-A740-01A | TCGA-LL-A740 | ATAD2B|ITSN2 | ATAD2B | ITSN2 | 2 | 2 | -1 | -1 | 2 | 1 | 1 | 0.15 | 24021008 | 24426652 | tier2 | Out-of-frame | 1585 | NA | 0.37292 |
LGG | TCGA-DU-6397-01A | TCGA-DU-6397 | ATAD2B|AC008073.5 | ATAD2B | AC008073.5 | 2 | 2 | -1 | -1 | 3 | 6 | 5 | 0.76 | 24092533 | 24290721 | tier1 | Out-of-frame | 1584 | non-validated | 0.34962 |
BRCA | TCGA-C8-A1HM-01A | TCGA-C8-A1HM | TRIM24|SVOPL | TRIM24 | SVOPL | 7 | 7 | 1 | -1 | 113 | 67 | 62 | 6 | 138258387 | 138281275 | tier1 | Out-of-frame | 18619 | NA | 0 |
BRCA | TCGA-A8-A08R-01A | TCGA-A8-A08R | TRIM24|ULK4 | TRIM24 | ULK4 | 7 | 3 | 1 | -1 | 5 | 2 | 2 | 0.4 | 138189153 | 41497086 | tier1 | In-frame | 18620 | NA | 0 |
LIHC | TCGA-DD-AACL-01A | TCGA-DD-AACL | TRIM24|BRAF | TRIM24 | BRAF | 7 | 7 | 1 | -1 | 9 | 2 | 2 | 0.74 | 138239609 | 140550012 | tier1 | In-frame | 18616 | NA | 0 |
LUAD | TCGA-55-8091-01A | TCGA-55-8091 | TRIM24|NTRK2 | TRIM24 | NTRK2 | 7 | 9 | 1 | 1 | 13 | 11 | 9 | 0.71 | 138258387 | 87482158 | tier1 | In-frame | 18618 | NA | 0 |
READ | TCGA-F5-6464-01A | TCGA-F5-6464 | TRIM24|BRAF | TRIM24 | BRAF | 7 | 7 | 1 | -1 | 7 | 4 | 4 | 0.74 | 138255748 | 140550012 | tier1 | In-frame | 18617 | NA | 0 |
CESC | TCGA-VS-A8QH-01A | TCGA-VS-A8QH | BAZ2B|SLC38A11 | BAZ2B | SLC38A11 | 2 | 2 | -1 | -1 | 2 | 2 | 1 | 0.32 | 160241666 | 165802237 | tier4 | Out-of-frame | 1948 | NA | 0.36068 |
CHOL | TCGA-W5-AA30-01A | TCGA-W5-AA30 | BAZ2B|PLA2R1 | BAZ2B | PLA2R1 | 2 | 2 | -1 | -1 | 4 | 1 | 1 | 0.21 | 160412334 | 160885474 | tier3 | 5UTR-CDS | 1947 | NA | 0.36728 |
LUSC | TCGA-85-A4JB-01A | TCGA-85-A4JB | BAZ2B|CYBRD1 | BAZ2B | CYBRD1 | 2 | 2 | -1 | 1 | 8 | 3 | 3 | 0.11 | 160472753 | 172398095 | tier1 | 5UTR-CDS | 1945 | NA | 0.36173 |
STAD | TCGA-BR-A4CR-01A | TCGA-BR-A4CR | BAZ2B|STK39 | BAZ2B | STK39 | 2 | 2 | -1 | -1 | 2 | 9 | 6 | 0.093 | 160412334 | 168931741 | tier4 | 5UTR-CDS | 1949 | NA | 0.37555 |
UCEC | TCGA-A5-A7WK-01A | TCGA-A5-A7WK | BAZ2B|ITGB6 | BAZ2B | ITGB6 | 2 | 2 | -1 | -1 | 3 | 3 | 3 | 1.4 | 160229556 | 161030650 | tier1 | Out-of-frame | 1946 | NA | 0.37417 |
BLCA | TCGA-DK-A3IS-01A | TCGA-DK-A3IS | NCOA3|DUSP15 | NCOA3 | DUSP15 | 20 | 20 | 1 | -1 | 5 | 2 | 2 | 1.7 | 46130763 | 30454956 | tier1 | 5UTR-5UTR | 11194 | NA | 0.37472 |
CESC | TCGA-LP-A5U3-01A | TCGA-LP-A5U3 | NCOA3|ARHGAP26 | NCOA3 | ARHGAP26 | 20 | 5 | 1 | 1 | 45 | 31 | 31 | 0.75 | 46256767 | 142601923 | tier1 | In-frame | 11193 | NA | 0.38438 |
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