Copy Number


The putative cancer-associated PDGs driven by SCNAs in each cancer type were identified by four criteria: 1) located in a peak region of a significantly recurrent focal SNCA locus estimated by the genomic identification of significant targets in cancer (GISTIC2) algorithm, (q≤0.25); 2) altered with high frequency and large amplitude (G-score ≥0.1); 3) mRNA reliably detected in at least 10% of tumor specimens in the given cancer type (90th percentile of FPKM value ≥1); and 4) mRNA significantly and positively correlated with copy numbers (Pearson P-value less than 0.001).


Pan-cancer level overall G-score of PDGs that recurrently gained or lost copy number in at least one cancer types

 Show   entries each page
 Jump to page  

 Total Page: 305 Total entries: 6083
 Showing page 305  first page | previous page | next page | last page 
Overall_Gscore No. of Cancer Types
 HGNC Symbol  Ensembl Gene ID  Amplification  Deletion  Amplification  Deletion 
GAD2ENSG00000136750  0.00    0.00    0    0  
OC90ENSG00000253117  0.00    0.00    0    0  
DRD3ENSG00000151577  0.00    0.00    0    0  

 Showing page 305 
first page | previous page | next page | last page 

Contact us | | Terms & Conditions.
Copyright © 2020 University of Pennsylvania. All Rights Reserved.